EVALUATING THE EFFECTS OF BILEVEL POSITIVE AIRWAY PRESSURE VERSUS CONVENTIONAL OXYGEN THERAPY FOR TREATMENT ACUTE CARDIOGENIC PULMONARY EDEMA

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HEMATI NASER; KAZERANI H.; REZAEI M.; ROSTAMI ARASH

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2009 | Volume:31 | Issue:66 Page(s): 6-13

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Title

EVALUATING THE EFFECTS OF BILEVEL POSITIVE AIRWAY PRESSURE VERSUS CONVENTIONAL OXYGEN THERAPY FOR TREATMENT ACUTE CARDIOGENIC PULMONARY EDEMA

Author(s)

HEMATI NASER | KAZERANI H. | REZAEI M. | ROSTAMI ARASH | Issue Writer Certificate

Keywords

ACUTE CARDIOGENIC PULMONARY EDEMAQ3

NON INVASIVE VENTILATIONQ3

BI-LEVEL POSITIVE AIRWAY PRESSUREQ3

CONTINUOUS POSITIVE AIRWAY PRESSUREQ3

Abstract

Background: Recent studies suggest the use of non-invasive ventilation in patients with ACUTE CARDIOGENIC PULMONARY EDEMA (ACPE). However, it remains unclear whether patients with ACPE benefit from non-invasive ventilation. This study designed to investigate short-term effects of non-invasive ventilation on respiratory, hemodynamic and oxygenation parameters in patients with respiratory failure due to ACPE and to identify need for intubation, recovery and admission.Materials and methods: In this randomized clinical trial study, 80 patients assigned to conventional oxygen therapy or non-invasive ventilation supplied by a standard ventilator through a face mask with mode of BI-LEVEL POSITIVE AIRWAY PRESSURE (BIPAP), in addition to standardized pharmacological treatment .Physiological parameters were obtained in 0, 15, 30, 60 minutes after non-invasive ventilation. The main end points were intubation and recorded recovery time (defined as oxygen saturation of 96% or more and respiratory rate less than 30 breaths/min and ICU stay.Results: Endotracheal intubation was required in one (2.5%) of 40 assigned non-invasive ventilation and in six (15%) of 40 assigned conventional therapy (p=0.1) recovery time was significantly shorter in the non-invasive ventilation group mean 42±9.9 vs 131±22.5 (p=0,0001) non-invasive ventilation led to a rapid improvement in oxygenation, respiratory rate, arterial PH, heart rate and blood pressure in the first hour (p=0.0001). There were significant differences in intensive care unit length of stay 2.8±1.2 days in non-invasive ventilation group vs. 4.8±1.5 in control group (p=0.0001). No hospital mortality was recorded.Conclusions: In this study of ACUTE CARDIOGENIC PULMONARY EDEMA non-invasive ventilation in mode of BIPAP was superior to conventional oxygen therapy. We suggest further studies to compare BI-LEVEL POSITIVE AIRWAY PRESSURE with CONTINUOUS POSITIVE AIRWAY PRESSURE NON INVASIVE VENTILATION on treatment in these patients.

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APA: Copy

HEMATI, NASER, KAZERANI, H., REZAEI, M., & ROSTAMI, ARASH. (2009). EVALUATING THE EFFECTS OF BILEVEL POSITIVE AIRWAY PRESSURE VERSUS CONVENTIONAL OXYGEN THERAPY FOR TREATMENT ACUTE CARDIOGENIC PULMONARY EDEMA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 31(66), 6-13. SID. https://sid.ir/paper/63248/en

Vancouver: Copy

HEMATI NASER, KAZERANI H., REZAEI M., ROSTAMI ARASH. EVALUATING THE EFFECTS OF BILEVEL POSITIVE AIRWAY PRESSURE VERSUS CONVENTIONAL OXYGEN THERAPY FOR TREATMENT ACUTE CARDIOGENIC PULMONARY EDEMA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2009;31(66):6-13. Available from: https://sid.ir/paper/63248/en

IEEE: Copy

NASER HEMATI, H. KAZERANI, M. REZAEI, and ARASH ROSTAMI, “EVALUATING THE EFFECTS OF BILEVEL POSITIVE AIRWAY PRESSURE VERSUS CONVENTIONAL OXYGEN THERAPY FOR TREATMENT ACUTE CARDIOGENIC PULMONARY EDEMA,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 31, no. 66, pp. 6–13, 2009, [Online]. Available: https://sid.ir/paper/63248/en

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