PREEMPTIVE NAPROXEN FOR PAIN RELIEF AFTER UPPER EXTREMITY SURGERY UNDER INTRAVENOUS REGIONAL ANESTHESIA

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DOROUDIAN M.R.; NOROOZI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2007 | Volume:29 | Issue:59 Page(s): 37-44

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Title

PREEMPTIVE NAPROXEN FOR PAIN RELIEF AFTER UPPER EXTREMITY SURGERY UNDER INTRAVENOUS REGIONAL ANESTHESIA

Author(s)

DOROUDIAN M.R. | NOROOZI M. | Issue Writer Certificate

Keywords

NAPROXENQ3

INTRAVENOUS REGIONAL ANESTHESIAQ3

POSTOPERATIVE PAINQ2

PREEMPTIVE ANALGESIAQ2

Abstract

Background: We evaluated efficacy of a single preoperative dose of oral vaproxen in reducing POSTOPERATIVE PAIN and analgesic requirement in patients undergoing upper etremity surgery under intavenous regional anesthesia (IVRA).Materials and Methods: Sixty healthy patients (ASA I-II) undergoing upper extremity surgery were randomly assigned into two groups. 90 minutes before operation, the treatment group (n=30) recieved enteric- coated tablet containing 500 mg of NAPROXEN, and the control group (n=30) recieved placebo. IVRA was achieved using 3mg/kg lidocaine diluted with saline to a total volume of 40 ml. Visual analogue scale (VAS) score at 0, 1, 2, 6, 12, and 24 hr after surgery, time to first analgesic requirement, total analgesic consumption in the first 24hr after operation, and side effects were noted.Results: VAS scores were lower in group NAPROXEN after torniquet release and in first 12hr after completion of surgery (p<0.05). First analgesic requirement time was longer in group NAPROXEN than group placebo (p<0.01). Postoperative analgesic requirement were significantly smaller in group NAPROXEN (p<0.01). Side effects were not seen in both groups.Conclusion: We conclude that a single preoperative dose of 500 mg NAPROXEN is effective in reducing POSTOPERATIVE PAIN in upper extremity surgery under IVRA, in the immediate postoperative up to 12hrs after the completion of surgery.

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APA: Copy

DOROUDIAN, M.R., & NOROOZI, M.. (2007). PREEMPTIVE NAPROXEN FOR PAIN RELIEF AFTER UPPER EXTREMITY SURGERY UNDER INTRAVENOUS REGIONAL ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 29(59), 37-44. SID. https://sid.ir/paper/63303/en

Vancouver: Copy

DOROUDIAN M.R., NOROOZI M.. PREEMPTIVE NAPROXEN FOR PAIN RELIEF AFTER UPPER EXTREMITY SURGERY UNDER INTRAVENOUS REGIONAL ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2007;29(59):37-44. Available from: https://sid.ir/paper/63303/en

IEEE: Copy

M.R. DOROUDIAN, and M. NOROOZI, “PREEMPTIVE NAPROXEN FOR PAIN RELIEF AFTER UPPER EXTREMITY SURGERY UNDER INTRAVENOUS REGIONAL ANESTHESIA,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 29, no. 59, pp. 37–44, 2007, [Online]. Available: https://sid.ir/paper/63303/en

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