DOES MICROALBUMINURIA PREDICT DURATION OF MECHANICAL VENTILATION IN CRITICAL ILL PATIENTS?

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SAFAVI M.R.; HONARMAND A.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2007 | Volume:29 | Issue:59 Page(s): 5-15

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Title

DOES MICROALBUMINURIA PREDICT DURATION OF MECHANICAL VENTILATION IN CRITICAL ILL PATIENTS?

Author(s)

SAFAVI M.R. | HONARMAND A. | Issue Writer Certificate

Keywords

INTENSIVE CARE UNITSQ2

MECHANICAL VENTILATIONQ2

MICROALBUMINURIA SEQUENTAL FAILURE ASSESSMENT (SOFA) SCOREQ3

Abstract

Background: To determine and incidence and presence of a relationship between predictors of microalbuminuria and duration of MECHANICAL VENTILATION (MV) in a general intensive care unit (ICU) patients and to compare the prognostic significance of microalbuminuria with known indicators such as the Sequential Organ Failure Assessment (SOFA) score.Materials and Methods: This study was a prospective observational study. The setting of study was Al-Zahra Medical Center ICU. Admitted critically ill patients were categorized by duration of MV to the group A (£7 days) and group 8 (>7 days). Any intervention was none. We measured serial spot urine albumin- creatinine ratios (ACR) on admission to ICU. (ACR-1), at 24, 72, 120 hrs after it and on the day of beginning or discontinuation from MV (ACR-2 or ACR-3). SOFA score was calculated on data at the time of admission to the ICU (SOFA-1), and on the days of starting or disconnection from MV (SOFA-2 or SOFA-3).Results: Seventy percent of patients had microalbuminuria and 63.3% had an ACR ³ 100mg/g admission. ACR-1 [mean (SE)] in patients group A and 8 was 30 (6) and 63 (16) mg/g respectively (p=0.0002), ACR-2 was 40 (4) and 52 (8), respectively (p=0.007), ACR-3 was 30 (11) and 44 (11) respectively (p=0.023). For all patients, mean (SE) ACR-2 fell from 37 (4) to 34 (8) mg/g at T3 (p<0.01). At T3, the SOFA score, significantly decreased compared with T2 (p<0.01) and there was also significant difference in this variables between patients in group A and 8 (p<0.05). For all patients, more than seven days duration of MV was significantly associated with SOFA score, UMA level, and ACR ratio on T1, and T3 (p<0.05).Conclusion: 80th the ACR and the SOFA score can be used together in estimating the risk of prolonged MV, even on the first day of admission of critically ill patients. It is also concluded that maintaining the level of UMA or ACR in normal range could shorten the duration of MV.

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APA: Copy

SAFAVI, M.R., & HONARMAND, A.. (2007). DOES MICROALBUMINURIA PREDICT DURATION OF MECHANICAL VENTILATION IN CRITICAL ILL PATIENTS?. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 29(59), 5-15. SID. https://sid.ir/paper/63304/en

Vancouver: Copy

SAFAVI M.R., HONARMAND A.. DOES MICROALBUMINURIA PREDICT DURATION OF MECHANICAL VENTILATION IN CRITICAL ILL PATIENTS?. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2007;29(59):5-15. Available from: https://sid.ir/paper/63304/en

IEEE: Copy

M.R. SAFAVI, and A. HONARMAND, “DOES MICROALBUMINURIA PREDICT DURATION OF MECHANICAL VENTILATION IN CRITICAL ILL PATIENTS?,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 29, no. 59, pp. 5–15, 2007, [Online]. Available: https://sid.ir/paper/63304/en

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