THE EFFICACY OF ENVIRONMENTAL AND VENTILATOR TUBES DISINFECTION BY H2O2 AND SILVER COMPOUNDS COMPARED WITH SODIUM HYPOCHLORITE AND GLUTARALDEHYDE IN THE ICU

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MOJTAHEDZADEH M.; YOUSEFSHAHI F.; KHAJAVI M.R.; NAJAFI A.; HADADI A.; AFHAMI SH.; AHMADI A.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2004 | Volume:25 | Issue:47 Page(s): 55-64

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Title

THE EFFICACY OF ENVIRONMENTAL AND VENTILATOR TUBES DISINFECTION BY H2O2 AND SILVER COMPOUNDS COMPARED WITH SODIUM HYPOCHLORITE AND GLUTARALDEHYDE IN THE ICU

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Keywords

SANSONILQ4

SODIUM HYPOCHLORITEQ4

GLUTARALDEHYDEQ4

VENTILATOR ASSOCIATED PNEUMONIAQ4

ICU ENVIRONMENT DISINFECTIONQ4

Abstract

Nosocomial infections (especially VENTILATOR ASSOCIATED PNEUMONIA) are the major cause of mortality in the ICU. It has been documented that the appropriate use of disinfectants and sterilants can help to control the incidence of nosocomial infection and reduces the morbidity and mortality and the costs.In this cross sectional open-label clinical trial we compare the efficacy of disinfecting of the environment (the surface of instruments) by SODIUM HYPOCHLORITE and ventilator tubes by GLUTARALDEHYDE and Sanosil (a disinfectant by the main composition of Silver and H2O2). For this reason positive cultures and the type of microorganisms in the microbial culture were detected.In sanosil group a considerable reduction was noted compared with SODIUM HYPOCHLORITE in frequency of total positive cultures (from 75.7% to 10.6%), gram positive bacteria (from 72.1% to 10.6%), and gram negative bacteria (from 9.0% to 0.0%), including pseudomonas (from 7.2% to 0.0%), and poly-microbial growths (from 12.6% to 0.96%), and also fungi (from 4.5 to 0.96%).In ventilator tubes there were no differences between cultures immediately after disinfection with Sanosil compared with GLUTARALDEHYDE. There was a reduction in positive cultures after at least 24 hours usage in total positive cultures (from 76.7% to 68.5%), two or poly-microbial growths (from 5.0.% to 33.3%), gram positive bacteria (from 60.0% to 51.8%), and gram negative bacteria (from 66.6% to 50.5), including Pseudomonas (from 66.7% to 18.5%), and an increase in the rate of Enterobacteriaceae (except of E.coli and Klebsiella) (from 0.0% to 24%) but only the latest two differences were meaningful.

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APA: Copy

MOJTAHEDZADEH, M., YOUSEFSHAHI, F., KHAJAVI, M.R., NAJAFI, A., HADADI, A., AFHAMI, SH., & AHMADI, A.. (2004). THE EFFICACY OF ENVIRONMENTAL AND VENTILATOR TUBES DISINFECTION BY H2O2 AND SILVER COMPOUNDS COMPARED WITH SODIUM HYPOCHLORITE AND GLUTARALDEHYDE IN THE ICU . JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 25(47), 55-64. SID. https://sid.ir/paper/63325/en

Vancouver: Copy

MOJTAHEDZADEH M., YOUSEFSHAHI F., KHAJAVI M.R., NAJAFI A., HADADI A., AFHAMI SH., AHMADI A.. THE EFFICACY OF ENVIRONMENTAL AND VENTILATOR TUBES DISINFECTION BY H2O2 AND SILVER COMPOUNDS COMPARED WITH SODIUM HYPOCHLORITE AND GLUTARALDEHYDE IN THE ICU . JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2004;25(47):55-64. Available from: https://sid.ir/paper/63325/en

IEEE: Copy

M. MOJTAHEDZADEH, F. YOUSEFSHAHI, M.R. KHAJAVI, A. NAJAFI, A. HADADI, SH. AFHAMI, and A. AHMADI, “THE EFFICACY OF ENVIRONMENTAL AND VENTILATOR TUBES DISINFECTION BY H2O2 AND SILVER COMPOUNDS COMPARED WITH SODIUM HYPOCHLORITE AND GLUTARALDEHYDE IN THE ICU ,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 25, no. 47, pp. 55–64, 2004, [Online]. Available: https://sid.ir/paper/63325/en

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