IS THE PROPOFOL EFFECTIVE ON POSTOPERATIVE ANALGESIC REQUIREMENT OF THE PATIENTS UNDER CABG IN ICU?

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AGHDAEE N.; FARASAT KISH R.; HYDARPOUR A.; MOLA SADEGHI ROKABADI GH.A.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2005 | Volume:27 | Issue:50 Page(s): 37-46

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Title

IS THE PROPOFOL EFFECTIVE ON POSTOPERATIVE ANALGESIC REQUIREMENT OF THE PATIENTS UNDER CABG IN ICU?

Author(s)

AGHDAEE N. | FARASAT KISH R. | HYDARPOUR A. | MOLA SADEGHI ROKABADI GH.A. | Issue Writer Certificate

Keywords

PROPOFOLQ3

ANALGESICQ3

CARDIAC ICUQ3

Abstract

Background: After coronary artery bypass graft (CABG) surgery and other open heart surgeries because of discontinuation of anesthetic drugs, during a short time after operation pain may start and it causes hemodynamic instability and ANALGESIC requirement of the patients. Also these patients need a period of controlled mechanical ventilation. To reduce hemodynamic instability and ANALGESIC requirement of the patients, short - acting sedative like PROPOFOL has been recommended. Materials and Methods: The present study performed as a prospective randomized clinical trial analysis on 50 patients after CABG surgery in Shahid Rajaii Hospital's ICU. Inclusion criteria included patients aged between 35-55 years, hemodynamic stability, ejection fraction more than 35% and exclusion criteria were patients with underlying and co-existing diseases and require intra-aortic balloon pump therapy after surgery. Premedication and anaesthetic drugs (PROPOFOL, sufentanil, atracurium) in all of patients were the same and standard. The patients were divided into two groups upon arrival in the ICU. The first group received sedative dose of PROPOFOL (group 1) and the other group received sedative dose of midazolam (group 2). Hemodynamic changes and sedative status all of these patients were monitored upon Ramsay sedation scale. Results: ANALGESIC requirement of patients in group 1 was 16% while 28% of patients in the group 2 needed ANALGESIC. There were no statistically significant differences (p>0.05) between two groups. Conclusion: There were no significant differences between the PROPOFOL and midazolam groups as far as the amount of ANALGESICs required postoperatively in CABG pateints. However it seems that PROPOFOL is a better sedative than midazolam in these patients.

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APA: Copy

AGHDAEE, N., FARASAT KISH, R., HYDARPOUR, A., & MOLA SADEGHI ROKABADI, GH.A.. (2005). IS THE PROPOFOL EFFECTIVE ON POSTOPERATIVE ANALGESIC REQUIREMENT OF THE PATIENTS UNDER CABG IN ICU?. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(50), 37-46. SID. https://sid.ir/paper/63355/en

Vancouver: Copy

AGHDAEE N., FARASAT KISH R., HYDARPOUR A., MOLA SADEGHI ROKABADI GH.A.. IS THE PROPOFOL EFFECTIVE ON POSTOPERATIVE ANALGESIC REQUIREMENT OF THE PATIENTS UNDER CABG IN ICU?. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2005;27(50):37-46. Available from: https://sid.ir/paper/63355/en

IEEE: Copy

N. AGHDAEE, R. FARASAT KISH, A. HYDARPOUR, and GH.A. MOLA SADEGHI ROKABADI, “IS THE PROPOFOL EFFECTIVE ON POSTOPERATIVE ANALGESIC REQUIREMENT OF THE PATIENTS UNDER CABG IN ICU?,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 50, pp. 37–46, 2005, [Online]. Available: https://sid.ir/paper/63355/en

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