A COMPARISON OF HEMODYNAMICS WAKE-UP TEST AND THE COSTS PROPOFOL- ALFENTANIL VERSUS PROPOFOL-REMIFENTANIL TOTAL INTRAVE-NOUS ANESTHESIA IN POSTERIOR SPINAL FUSION

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IMANI F.; JAFARIAN A.K.; HASANI V.A.

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Paper Information

Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2006 | Volume:28 | Issue:53 Page(s): 14-22

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Title

A COMPARISON OF HEMODYNAMICS WAKE-UP TEST AND THE COSTS PROPOFOL- ALFENTANIL VERSUS PROPOFOL-REMIFENTANIL TOTAL INTRAVE-NOUS ANESTHESIA IN POSTERIOR SPINAL FUSION

Author(s)

IMANI F. | JAFARIAN A.K. | HASANI V.A. | Issue Writer Certificate

Keywords

POSTERIOR SPINAL FUSIONQ3

WAKE-UP TESTQ4

PROPOFOL - ALFENTANILQ3

PROPOFOL - RENIFENTAUILQ3

Abstract

Background: WAKE-UP TEST can be used during POSTERIOR SPINAL FUSION (PSF) to ensure that spinal function remains intact. The goals of this study were assessment of hemodynamic changes, WAKE-UP TEST times and their quality, and costs between propofol alfentanil (PA) versus propofol-remifentanil (PR) total intravenous anesthesia (TIVA) during PSF surgery.Material and Methods: 40 patients with scoliosis who were candidates for PSF surgery randomly allocated in either alfentanil (PA) or remifentanil (PR) groups. After intravnous premedication with midzaolam 30µg/kg in both groups, and alfentanil 30µg/kg in PA group and remifentanil 1µg/kg in PR group, anesthesia was induced with thiopental 5 mg/kg and atracurium 0.6 mg/kg 2 minutes later trachea was intubated. Then atracurium 0.2 mg/kg was given every 20 minutes PA group was infused with alfentanil 1µg/kg/min and in PR group infusion of remifentanil 0.2µg/kg/min was given propofol 50µg/kg/min was given to all patients. At the surgeon's request, infusions were discontinued. Patients were asked to move their hands and feet, and then their anesthetic protocol was continued again. The duration of anesthetic discontinuation to the times when spontaneous respiration was started (T1) and, the hands and feet movement (T2) were recorded. We also compared the hemodynamic changes and the costs of drugs between the two groups. Results: Average of blood predsure and heart rate were lower in PR group than PA group (p<0.01 and p<0.05, respectively). Hypotensive agents requirement was also less in remifentanil group (p<0.001). The average T1 and T2 were significantly shorter in PR group (3.6±2.5 and 4.1±2 min) than PA group (6.1±4 and 7.5±4.5 min) (p<0.01). Quality of WAKE-UP TEST was not different. The cost was more in PR group than PA group (p<0.01).Conclusion: During POSTERIOR SPINAL FUSION the use of propofol-remifentanil infusion in comparison to propofol-alfentanil infusion not only makes the conduction of WAKE-UP TEST faster, but also by lowering the patient's blood pressure decreases the need of hypotensive agents.

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APA: Copy

IMANI, F., JAFARIAN, A.K., & HASANI, V.A.. (2006). A COMPARISON OF HEMODYNAMICS WAKE-UP TEST AND THE COSTS PROPOFOL- ALFENTANIL VERSUS PROPOFOL-REMIFENTANIL TOTAL INTRAVE-NOUS ANESTHESIA IN POSTERIOR SPINAL FUSION. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 28(53), 14-22. SID. https://sid.ir/paper/63370/en

Vancouver: Copy

IMANI F., JAFARIAN A.K., HASANI V.A.. A COMPARISON OF HEMODYNAMICS WAKE-UP TEST AND THE COSTS PROPOFOL- ALFENTANIL VERSUS PROPOFOL-REMIFENTANIL TOTAL INTRAVE-NOUS ANESTHESIA IN POSTERIOR SPINAL FUSION. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2006;28(53):14-22. Available from: https://sid.ir/paper/63370/en

IEEE: Copy

F. IMANI, A.K. JAFARIAN, and V.A. HASANI, “A COMPARISON OF HEMODYNAMICS WAKE-UP TEST AND THE COSTS PROPOFOL- ALFENTANIL VERSUS PROPOFOL-REMIFENTANIL TOTAL INTRAVE-NOUS ANESTHESIA IN POSTERIOR SPINAL FUSION,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 28, no. 53, pp. 14–22, 2006, [Online]. Available: https://sid.ir/paper/63370/en

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