COMPARATIVE STUDY OF THE EFFECT OF INTRAVENOUS MIDAZOLAM PREMEDICATION ON THE INTRAOCULAR PRESSURE IN INTRAOCULAR SURGERIES

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HESHMATI F.; ZEYNALI M.B.; SHARIFI N.; ABBASIVASH R.; MAHOURI A.R.; RAFAATI M.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2003 | Volume:24 | Issue:43 Page(s): 17-22

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Title

COMPARATIVE STUDY OF THE EFFECT OF INTRAVENOUS MIDAZOLAM PREMEDICATION ON THE INTRAOCULAR PRESSURE IN INTRAOCULAR SURGERIES

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Keywords

PREMEDICATIONQ3

MIDAZOLAMQ3

INTRAOCULAR PRESSUREQ4

Abstract

Considering the existing conflicted results of previous studies regarding to the effect of MIDAZOLAM on IOP, we decided to study the effect of MIDAZOLAM PREMEDICATION on INTRAOCULAR PRESSURE (lOP).In a double blinded clinical trial, 40 patients ASAI, (50-70 years old), that were scheduled for cataract extraction under general anesthesia were divided into two separate groups, study group (A) in which patients received MIDAZOLAM 0.03 mg/Kg IV as premedicatin and control group (B) in which patients received 2ml normal saline as a placebo at random. At regular intervals, the changes in vital signs and lOP were measured.In the study group, lOP decreased about 8.4% whereas; it increased almost 9.4% in control group (p<0.05). Likewise, the changes of vital signs in the two groups were in reverse direction (increase in control group vs. decrease in study group); systolic blood pressure 6.7% increase vs. 10% decrease, diastolic blood pressure 8% increase vs. 10% decrease and heart rate 8.5% increase vs. 5.4% decrease (p<0.05).This study shows that intravenous administration of MIDAZOLAM 5 min prior to induction of general anesthesia, is an effective and safe method for reduction of lOP and can be used easily in intraocular procedures.

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APA: Copy

HESHMATI, F., ZEYNALI, M.B., SHARIFI, N., ABBASIVASH, R., MAHOURI, A.R., & RAFAATI, M.. (2003). COMPARATIVE STUDY OF THE EFFECT OF INTRAVENOUS MIDAZOLAM PREMEDICATION ON THE INTRAOCULAR PRESSURE IN INTRAOCULAR SURGERIES. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 24(43), 17-22. SID. https://sid.ir/paper/63376/en

Vancouver: Copy

HESHMATI F., ZEYNALI M.B., SHARIFI N., ABBASIVASH R., MAHOURI A.R., RAFAATI M.. COMPARATIVE STUDY OF THE EFFECT OF INTRAVENOUS MIDAZOLAM PREMEDICATION ON THE INTRAOCULAR PRESSURE IN INTRAOCULAR SURGERIES. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2003;24(43):17-22. Available from: https://sid.ir/paper/63376/en

IEEE: Copy

F. HESHMATI, M.B. ZEYNALI, N. SHARIFI, R. ABBASIVASH, A.R. MAHOURI, and M. RAFAATI, “COMPARATIVE STUDY OF THE EFFECT OF INTRAVENOUS MIDAZOLAM PREMEDICATION ON THE INTRAOCULAR PRESSURE IN INTRAOCULAR SURGERIES,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 24, no. 43, pp. 17–22, 2003, [Online]. Available: https://sid.ir/paper/63376/en

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