A COMPRAISON OF THE HYPERDYNAMIC EFFECTS OF HYPERTONIC SALINE 7.5% AND NORMAL SALINE 0.9% ADMINISTERED AS PREBLOCK FLUIDS DURING SPINAL ANESTHESIA

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AKBARINEZHAD MOUSAVI S.M.; HOSSEINKHAN ZAHED; AKBARIAN F.; EGHTESADI ARAGHI P.

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Paper Information

Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2003 | Volume:24 | Issue:43 Page(s): 23-31

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Title

A COMPRAISON OF THE HYPERDYNAMIC EFFECTS OF HYPERTONIC SALINE 7.5% AND NORMAL SALINE 0.9% ADMINISTERED AS PREBLOCK FLUIDS DURING SPINAL ANESTHESIA

Author(s)

AKBARINEZHAD MOUSAVI S.M. | HOSSEINKHAN ZAHED | AKBARIAN F. | EGHTESADI ARAGHI P. | Issue Writer Certificate

Keywords

HYPERTOINC SALINE 7.5%Q4

NORMAL SALINE 0.9%Q4

PREBLOCK HYDRATIONQ3

SPINAL ANESTHESIAQ3

Abstract

In a randomized double blind clinical trial, 100 patients with ASA physical status I and II who underwent lower abdominal or lower extremities surgery under SPINAL ANESTHESIA, were randomly allocated into two groups. In hypertonic saline (HS) group, 1.6 ml/Kg of hypertonic saline and in normal saline (NS) group 13 ml/Kg were infused as fluids for hydration prior to block, for initial fluid administration, thus all the patients received equal amounts of sodium (2mmol/Kg). Heart rate, mean arterial blood pressure, Na, Cl, K and Osmolality were measured at 5 points: 1. Before injection of Pretreatment, 2. After injection of Pretreatment, 3. After SPINAL ANESTHESIA, 4. After the end of surgery, 5. After recovery from anesthesia (Dorsiflesxion, Plantar flexion of both toes). Demographic parameters, duration, level of SPINAL ANESTHESIA, heart rate, MAP and injected ephedrin had no statistically significant differences. In both groups there were significant increases in HR and systolic blood pressure (p<0.01). In HS group NA, Cl, and osmolality increased significantly (p<0.01). There were no significant changes in K in both groups. Injected volumes in HS group were significantly less than the NS group (p<0.01).Generally, hemodynamic effects of 7.5% hypertonic saline are similar to normal saline, but patients with compromised cardiovascular system in whom adminstration could not be tolerated or in situations where there is not enough time or a patent line for injection does not exist, hypertonic saline is a better choice than normal saline.

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APA: Copy

AKBARINEZHAD MOUSAVI, S.M., HOSSEINKHAN, ZAHED, AKBARIAN, F., & EGHTESADI ARAGHI, P.. (2003). A COMPRAISON OF THE HYPERDYNAMIC EFFECTS OF HYPERTONIC SALINE 7.5% AND NORMAL SALINE 0.9% ADMINISTERED AS PREBLOCK FLUIDS DURING SPINAL ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 24(43), 23-31. SID. https://sid.ir/paper/63378/en

Vancouver: Copy

AKBARINEZHAD MOUSAVI S.M., HOSSEINKHAN ZAHED, AKBARIAN F., EGHTESADI ARAGHI P.. A COMPRAISON OF THE HYPERDYNAMIC EFFECTS OF HYPERTONIC SALINE 7.5% AND NORMAL SALINE 0.9% ADMINISTERED AS PREBLOCK FLUIDS DURING SPINAL ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2003;24(43):23-31. Available from: https://sid.ir/paper/63378/en

IEEE: Copy

S.M. AKBARINEZHAD MOUSAVI, ZAHED HOSSEINKHAN, F. AKBARIAN, and P. EGHTESADI ARAGHI, “A COMPRAISON OF THE HYPERDYNAMIC EFFECTS OF HYPERTONIC SALINE 7.5% AND NORMAL SALINE 0.9% ADMINISTERED AS PREBLOCK FLUIDS DURING SPINAL ANESTHESIA,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 24, no. 43, pp. 23–31, 2003, [Online]. Available: https://sid.ir/paper/63378/en

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