COMPARING THE EFFECT OF HALOTHANE AND ISOFLURANE IN COMBINATION AND ALONE FOR CONTROLLED HYPOTENSION IN SPINAL COLUMN SURGERIES

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FARBOUD A.; GHAFARIPOUR S.; AMINI A.; ZAHOORI K.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2005 | Volume:27 | Issue:52 Page(s): 22-29

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Title

COMPARING THE EFFECT OF HALOTHANE AND ISOFLURANE IN COMBINATION AND ALONE FOR CONTROLLED HYPOTENSION IN SPINAL COLUMN SURGERIES

Author(s)

FARBOUD A. | GHAFARIPOUR S. | AMINI A. | ZAHOORI K. | Issue Writer Certificate

Keywords

ISOFLURANEQ2

HYOTENSIONQ3

CONTROLLEDQ2

HALOTHANEQ2

Abstract

Background: Deliberate hypotension by different methods is a useful technique in anesthesia. This technique by decreasing bleeding provides a better surgical field while reducing the need for allogenic blood transfusion. One method is to use the inhalational anesthetics. In the present research HALOTHANE and ISOFLURANE, each one alone and in combination have been compared regarding their arterial blood pressure reducing effect. The aim of this research is to find a simple and suitable technique for blood pressure reduction during surgery. Materials & Methods: Sixty spinal column surgery patients (duration of surgeries: 1-3 hrs), with ASA physical status class one and between 19-44 yrs of age, were allocated randomly to three groups (20 in each). All of the patients were operated by one surgeon. Induction of anesthesia was similar for all patients. Then maintenance phase of anesthesia was started differently in each group as: Group 1: HALOTHANE (1.2 MAC) + Nitrous oxide (50%) + Oxygen (50%)Group 2: ISOFLURANE (1.2 MAC) + Nitrous oxide (50%) + Oxygen (50%)Group 3: HALOTHANE (0.6 MAC) + ISOFLURANE (0.6 MAC) + Nitrous oxide (50%) + Oxygen (50%)The patients' blood pressures were measured from the beginning of anesthesia till the end of the surgery by "NIBP" (non. invasive blood pressure) monitoring every 5 minutes. The recorded data were analyzed by one-way analysis of variance (one-way ANOVA) and Scheff's paired compare means tests.Results: The results showed that the mean arterial blood pressure has greater drop in group 3 (halothane + ISOFLURANE comparing groups 1 and 2 (p values 0.04% and 0.014 respectively).Conclusion: It can be concluded that the blood pressure lowering effect of HALOTHANE and ISOFLURANE in combination is more effective than ISOFLURANE of HALOTHANE alone.

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APA: Copy

FARBOUD, A., GHAFARIPOUR, S., AMINI, A., & ZAHOORI, K.. (2005). COMPARING THE EFFECT OF HALOTHANE AND ISOFLURANE IN COMBINATION AND ALONE FOR CONTROLLED HYPOTENSION IN SPINAL COLUMN SURGERIES. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(52), 22-29. SID. https://sid.ir/paper/63445/en

Vancouver: Copy

FARBOUD A., GHAFARIPOUR S., AMINI A., ZAHOORI K.. COMPARING THE EFFECT OF HALOTHANE AND ISOFLURANE IN COMBINATION AND ALONE FOR CONTROLLED HYPOTENSION IN SPINAL COLUMN SURGERIES. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2005;27(52):22-29. Available from: https://sid.ir/paper/63445/en

IEEE: Copy

A. FARBOUD, S. GHAFARIPOUR, A. AMINI, and K. ZAHOORI, “COMPARING THE EFFECT OF HALOTHANE AND ISOFLURANE IN COMBINATION AND ALONE FOR CONTROLLED HYPOTENSION IN SPINAL COLUMN SURGERIES,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 52, pp. 22–29, 2005, [Online]. Available: https://sid.ir/paper/63445/en

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