EVALUATION OF THE ANALGESIC EFFECTS OF TWO DOSES OF VERAPAMIL ADDED TO BUPIVACAINE COMPARED WITH BUPIVACAINE ALONE IN INTERSCALENE BLOCK

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MOSAFA F.; SALIMI A.R.; RASTI A.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2006 | Volume:27 | Issue:51 Page(s): 22-28

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Title

EVALUATION OF THE ANALGESIC EFFECTS OF TWO DOSES OF VERAPAMIL ADDED TO BUPIVACAINE COMPARED WITH BUPIVACAINE ALONE IN INTERSCALENE BLOCK

Author(s)

MOSAFA F. | SALIMI A.R. | RASTI A. | Issue Writer Certificate

Keywords

LOCAL ANESTHETICQ4

INTERSCALENE BLOCKQ3

VERAPAMILQ4

ONSET OF BLOCKQ4

Abstract

Background: Adjuvant drugs have been proposed to be accompanied with LOCAL ANESTHETICs to decrease ONSET OF BLOCK and increase duration of block and analgesic efficacy. In this study VERAPAMIL has been added to bupivacaine to assess its additive analgesic effect in INTERSCALENE BLOCK. Materials and Methods: In a double blinded descriptive analytical clinical trial 60 patients aged 18-40 years and ASA Class I-II were allocated randomly into three groups. In group (a) block was performed merely with bupivacaine (30cc) and 2cc normal saline. In group (b) block was performed with bupivacaine and 2.5mg VERAPAMIL and in group (c) with 30cc bupivacaine and 5mg VERAPAMIL. Onset of sensory block, motor block and total analgesia and also blood pressure and heart rate were assessed in all groups. Statistical analytic tests were used for data analysis. SPSS software (version 11.5) was used for analysis. P<0.05 was considered statistically significant. Results: Our results clarified that VERAPAMIL decreased the onset time of anesthesia, motor block and total analgesia but there were not any statistically difference between adding 2.5 and 5mg VERAPAMIL to bupivacaine, (p<0.05). No variation more than 200A, from baseline was detected in blood pressure and heart rate among patients who received bupivacaine plus VERAPAMIL. Conclusion: It seems that VERAPAMIL could be an effective adjuvant for bupivacaine in INTERSCALENE BLOCK compared with bupivacaine administered alone, as far as the decrease in onset time of analgesia and anesthesia is concerned.

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APA: Copy

MOSAFA, F., SALIMI, A.R., & RASTI, A.. (2006). EVALUATION OF THE ANALGESIC EFFECTS OF TWO DOSES OF VERAPAMIL ADDED TO BUPIVACAINE COMPARED WITH BUPIVACAINE ALONE IN INTERSCALENE BLOCK. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(51), 22-28. SID. https://sid.ir/paper/63460/en

Vancouver: Copy

MOSAFA F., SALIMI A.R., RASTI A.. EVALUATION OF THE ANALGESIC EFFECTS OF TWO DOSES OF VERAPAMIL ADDED TO BUPIVACAINE COMPARED WITH BUPIVACAINE ALONE IN INTERSCALENE BLOCK. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2006;27(51):22-28. Available from: https://sid.ir/paper/63460/en

IEEE: Copy

F. MOSAFA, A.R. SALIMI, and A. RASTI, “EVALUATION OF THE ANALGESIC EFFECTS OF TWO DOSES OF VERAPAMIL ADDED TO BUPIVACAINE COMPARED WITH BUPIVACAINE ALONE IN INTERSCALENE BLOCK,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 51, pp. 22–28, 2006, [Online]. Available: https://sid.ir/paper/63460/en

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