SPECIES & STRAINS IDENTIFICATION OF LEISHMANIA ISOLATED FROM KALA- AZAR PATIENTS IN NORTHWEST OF IRAN

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MAZLUMI A.; ESMAEILI H.; DAVIES C.

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Journal: Studies in Medical Sciences Year:2004 | Volume:15 | Issue:1 Page(s): 39-46

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Title

SPECIES & STRAINS IDENTIFICATION OF LEISHMANIA ISOLATED FROM KALA- AZAR PATIENTS IN NORTHWEST OF IRAN

Author(s)

MAZLUMI A. | ESMAEILI H. | DAVIES C. | Issue Writer Certificate

Keywords

LEISHMANIAQ3

ISOENZYMESQ4

ELECTROPHORESISQ3

KALA AZARQ4

Abstract

Background & Aim: LEISHMANIAsis is a general name given to disease caused by any member of protozoan genus LEISHMANIA and. can be divided into visceral (kala-azar), cutaneous and mucosal syndromes. For epidemiologic studies, identification of strains & species of lesihmania protozoan in any endemic area is a necessity. The aim of this study characterization of LEISHMANIA isolate from patient with kala-azar based on ISOENZYMES electrophoretic patterns & determination of the main reservoir, deduction from comparison of isoenzyme pattern of reservoir& patients in northwest of Iran were undertaken. Materials & Methods: Twenty one bone marrow aspirated were obtained from patients and after inoculation in semisolid sloppy evane's N.N.N meida electrophoresed by a thin-layer starch gel method for twelve ISOENZYMES. Results: The isoenzyme profiles of all patients were indistinguishable from L. Infantam LON-49= [MON-1] zymodeme (MHOM/TN/80/IPT1) and are the same profiles which previously were identified in naturally infected dogs in northwest of Iran. So while the species of LEISHMANIA was proved. The main reservoir also was identified. Discussion: This study again proved that kala-azar northwest of Iran is a Mediterranean site of kala-azar.

Cites

A CASE SERIES STUDY ON CLINICAL AND EPIDEMIOLOGIC ASPECTS OF KALA AZAR IN PATIENTS REFERRED TO THE CHILDREN'S MEDICAL CENTER SINCE 1991 TO 2003

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APA: Copy

MAZLUMI, A., ESMAEILI, H., & DAVIES, C.. (2004). SPECIES & STRAINS IDENTIFICATION OF LEISHMANIA ISOLATED FROM KALA- AZAR PATIENTS IN NORTHWEST OF IRAN . STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 15(1), 39-46. SID. https://sid.ir/paper/63510/en

Vancouver: Copy

MAZLUMI A., ESMAEILI H., DAVIES C.. SPECIES & STRAINS IDENTIFICATION OF LEISHMANIA ISOLATED FROM KALA- AZAR PATIENTS IN NORTHWEST OF IRAN . STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2004;15(1):39-46. Available from: https://sid.ir/paper/63510/en

IEEE: Copy

A. MAZLUMI, H. ESMAEILI, and C. DAVIES, “SPECIES & STRAINS IDENTIFICATION OF LEISHMANIA ISOLATED FROM KALA- AZAR PATIENTS IN NORTHWEST OF IRAN ,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 15, no. 1, pp. 39–46, 2004, [Online]. Available: https://sid.ir/paper/63510/en

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