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Information Journal Paper

Title

HEALING EFFECT OF INDUCTION OF DIRECT ELECTRIC CURRENTS PLUS SELENIUM AND SILVER NANOPARTICLE ON SKIN LESIONS CAUSED BYLEISHMANIAL MAJOR IN BALB/C MICE

Pages

  828-835

Abstract

 Background & Aims: Various Leishmania species can cause human infection with a spectrum of clinical manifestations. The current treatments are unsatisfactory; and in absence of a vaccine there is an urgent need for effective drugs to replace those currently in use. In the present study, the effect of direct current electricity in combination with SELENIUM AND SILVER NANOPARTICLES on the healing of leishmanial lesions has been investigated.Materials & Methods: In this experimental study, 24 Balb/c MICE were divided into four groups and infected experimentally with L.major. Then silver nanoparticles with a concentration of 250 mg/kg and selenium nanoparticle with a concentration of 125 mg/kg were injected inter-lesion, and simultaneously 0.5 mA DC induction was applied directly into the wound. Finally, the lesion size and MICE body weight changes were measured during five weeks.Results: The lesions were found to be smaller in the group treated with DC and silver nanoparticles than the group treated with DC and selenium nanoparticles (P<0.05). Two treated groups showed significant differences with both negative control group and the group treated with Glucantime (P<0.05).Conclusion: The results showed that SELENIUM AND SILVER NANOPARTICLES with direct current electricity promotes wound healing in MICE.

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    APA: Copy

    KARIMI, MEHDI, DALIMI, ABDOLHOSSEIN, Jameie, Farnoosh, DALIMI, ABAS, & GHAFARIFAR, FATEMEH. (2016). HEALING EFFECT OF INDUCTION OF DIRECT ELECTRIC CURRENTS PLUS SELENIUM AND SILVER NANOPARTICLE ON SKIN LESIONS CAUSED BYLEISHMANIAL MAJOR IN BALB/C MICE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 26(10), 828-835. SID. https://sid.ir/paper/63577/en

    Vancouver: Copy

    KARIMI MEHDI, DALIMI ABDOLHOSSEIN, Jameie Farnoosh, DALIMI ABAS, GHAFARIFAR FATEMEH. HEALING EFFECT OF INDUCTION OF DIRECT ELECTRIC CURRENTS PLUS SELENIUM AND SILVER NANOPARTICLE ON SKIN LESIONS CAUSED BYLEISHMANIAL MAJOR IN BALB/C MICE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2016;26(10):828-835. Available from: https://sid.ir/paper/63577/en

    IEEE: Copy

    MEHDI KARIMI, ABDOLHOSSEIN DALIMI, Farnoosh Jameie, ABAS DALIMI, and FATEMEH GHAFARIFAR, “HEALING EFFECT OF INDUCTION OF DIRECT ELECTRIC CURRENTS PLUS SELENIUM AND SILVER NANOPARTICLE ON SKIN LESIONS CAUSED BYLEISHMANIAL MAJOR IN BALB/C MICE,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 26, no. 10, pp. 828–835, 2016, [Online]. Available: https://sid.ir/paper/63577/en

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