NONINVASIVE EVALUATION OF MYOCARDIAL SYSTOLIC DYSFUNCTION IN THE EARLY STAGE OF KAWASAKI DISEASE: A SPECKLE-TRACKING ECHOCARDIOGRAPHY STUDY

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HEMATIAN M.N.; TORABI S.; MALAKAN RAD E.; SAYADPOUR ZANJANI K.

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Journal Paper

Paper Information

Journal: Iranian Journal of Pediatrics Year:2014 | Volume:24 | Issue:2 (SUPPLEMENT) Page(s): 3-3

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Title

NONINVASIVE EVALUATION OF MYOCARDIAL SYSTOLIC DYSFUNCTION IN THE EARLY STAGE OF KAWASAKI DISEASE: A SPECKLE-TRACKING ECHOCARDIOGRAPHY STUDY

Author(s)

HEMATIAN M.N. | TORABI S. | MALAKAN RAD E. | SAYADPOUR ZANJANI K. | Issue Writer Certificate

Keywords

KAWASAKI DISEASE

LEFT VENTRICULAR FUNCTION

MYOCARDIAL VELOCITY

STRAIN RATE IMAGING

Abstract

Background: Evaluation of myocardial function by speckle-tracking echocardiography is a new method for the early diagnosis of systolic dysfunction. We aimed to determine myocardial speckle-tracking echocardiography indices in KAWASAKI DISEASE (KD) patients and compare them with the same indices in control subjects.Methods: Thirty-two patients (65.5% male) with KD and 19 control subjects with normal echocardiography participated in this study. After their demographic characteristics and clinical findings were recorded, all the participants underwent transthoracic echocardiography. Strain (S), Strain rate (SR), time to peak strain (TPS), and Strain rate (TPSR), Longitudinal velocity and view point velocity images in the two-, three-, and four-chamber views were semi-automatically obtained via speckle-tracking echocardiography.Findings: Among the patients, 24 (75%) were younger than 4 years old. Mean global S and SR was significantly reduced in the KD patients compared to controls (17.03±1.28 vs.20.22±2.14% and 1.66±0.16 vs.1.97±0.25 1/s, respectively), while there were no significant differences regarding mean TPS, TPSR, Longitudinal velocity and view point velocity. Using repeated measure of analysis of variances, we observed that S and SR decreased from base to apical level in both groups. The change in the pattern of age adjusted mean S and SR across levels was significantly different between the groups (P<0.001 for both parameters).Conclusion: We showed changes in S and SR in KD patients versus control subjects in the acute phase of KD. However, we suggest that further studies be undertaken to compare S and SR in the acute phase and thereafter in KD patients.

Cites

KAWASAKI DISEASE AND PERIPHERAL GANGRENE IN INFANCY (CASE REPORT)

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APA: Copy

HEMATIAN, M.N., TORABI, S., MALAKAN RAD, E., & SAYADPOUR ZANJANI, K.. (2014). NONINVASIVE EVALUATION OF MYOCARDIAL SYSTOLIC DYSFUNCTION IN THE EARLY STAGE OF KAWASAKI DISEASE: A SPECKLE-TRACKING ECHOCARDIOGRAPHY STUDY. IRANIAN JOURNAL OF PEDIATRICS, 24(2 (SUPPLEMENT)), 3-3. SID. https://sid.ir/paper/641288/en

Vancouver: Copy

HEMATIAN M.N., TORABI S., MALAKAN RAD E., SAYADPOUR ZANJANI K.. NONINVASIVE EVALUATION OF MYOCARDIAL SYSTOLIC DYSFUNCTION IN THE EARLY STAGE OF KAWASAKI DISEASE: A SPECKLE-TRACKING ECHOCARDIOGRAPHY STUDY. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2014;24(2 (SUPPLEMENT)):3-3. Available from: https://sid.ir/paper/641288/en

IEEE: Copy

M.N. HEMATIAN, S. TORABI, E. MALAKAN RAD, and K. SAYADPOUR ZANJANI, “NONINVASIVE EVALUATION OF MYOCARDIAL SYSTOLIC DYSFUNCTION IN THE EARLY STAGE OF KAWASAKI DISEASE: A SPECKLE-TRACKING ECHOCARDIOGRAPHY STUDY,” IRANIAN JOURNAL OF PEDIATRICS, vol. 24, no. 2 (SUPPLEMENT), pp. 3–3, 2014, [Online]. Available: https://sid.ir/paper/641288/en

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