STUDY OF GENES AS BIOMARKERS IN DISTINGUISH CANCEROUSFROM NORMAL TISSUE SAMPLES IN PROSTATE CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAMAZI SHAHIN; FASIHI ALI; ABOLHASSANI MARZIYE; IZIY ELHAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Studies in Medical Sciences Year:2016 | Volume:27 | Issue:6 Page(s): 523-532

Download Full-Text

Persian Verion

View:

1,046

Download:

Cites:

Information Journal Paper

Title

STUDY OF GENES AS BIOMARKERS IN DISTINGUISH CANCEROUSFROM NORMAL TISSUE SAMPLES IN PROSTATE CANCER

Author(s)

RAMAZI SHAHIN | FASIHI ALI | ABOLHASSANI MARZIYE | IZIY ELHAM | Issue Writer Certificate

Keywords

PROSTAT CANCERQ2

BIOMARKERQ1

GENE EXPRESSIONQ2

Abstract

Background & Aims: Prostate cancer (PCa) is the second most common cancer in men worldwide. The identification of sensitive and specific BIOMARKERs in tissue and serum is of utmost importance to reduce the mortality of prostate cancer. Since that, early detection of cancer has an important role in treatment, in this study we tried to identify genes that could potentially effective in early screening for prostate cancer. Using logistic regression, suitable model to screen tumor samples from normal samples was designed.Materials & Methods: In this study, GENE EXPRESSION data of metastatic and non-metastatic cancer samples and normal prostate samples were collected from the NCBI database. By examining the expression level of genes in these samples, valuable genes for screening were identified.Results: Using logistic regression two model were designed based on the increase or decrease in the expression of genes. The Area under the curve, sensitivity and specificity for the first model were, respectively, 0.968, 0.911 and 0.914 and for the second model 0.991, 0.951 and 0.956, respectively.Conclusion: Due to the high value of sensitivity and specificity in the designed models, studied Genes have the potential for screening prostate cancer in the early stages and metastasis stages of cancer.

Cites

No record.

References

Cite

APA: Copy

RAMAZI, SHAHIN, FASIHI, ALI, ABOLHASSANI, MARZIYE, & IZIY, ELHAM. (2016). STUDY OF GENES AS BIOMARKERS IN DISTINGUISH CANCEROUSFROM NORMAL TISSUE SAMPLES IN PROSTATE CANCER. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 27(6), 523-532. SID. https://sid.ir/paper/64217/en

Vancouver: Copy

RAMAZI SHAHIN, FASIHI ALI, ABOLHASSANI MARZIYE, IZIY ELHAM. STUDY OF GENES AS BIOMARKERS IN DISTINGUISH CANCEROUSFROM NORMAL TISSUE SAMPLES IN PROSTATE CANCER. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2016;27(6):523-532. Available from: https://sid.ir/paper/64217/en

IEEE: Copy

SHAHIN RAMAZI, ALI FASIHI, MARZIYE ABOLHASSANI, and ELHAM IZIY, “STUDY OF GENES AS BIOMARKERS IN DISTINGUISH CANCEROUSFROM NORMAL TISSUE SAMPLES IN PROSTATE CANCER,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 27, no. 6, pp. 523–532, 2016, [Online]. Available: https://sid.ir/paper/64217/en

Related Journal Papers