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Information Journal Paper

Title

EFFECTIVENESS OF ORAL VITAMIN E ON SERUM LIPOPROTEINS OF PATIENTS WITH CORONARY ARTERY DISEASE

Pages

  107-114

Abstract

 Background & Aim: VITAMIN E has an antioxidant effect and recommended for patients with CORONARY ARTERY DISEASE (CAD), with dosage of 100mg/day. The antilipidemic effect of VITAMIN E is contraversial. This study planned for evaluation of antilipidemic effect of VITAMIN E on serum lipoproteins.Material & Methods: In this double blind, Placebo controlled clinical trial, we selected 108 consecutive patients (mean age 57:1:.7.2) with CAD and basal low density lipoprotein cholestol (LDL-c) level of 100-130mg/dl, and randomised in two groups, 58 patients in case group and 50 in control group. Case group received protocol of non pharmacological treatment plus 1 tablet of 100mg VITAMIN E per day, and control group received protocol of nonpharmacological treatment plus 1 tablet of placebo. After I month period lipid profile was measured two time for 1 week apart after 10 hours fasting periods, and mean level was detected. Data analysed statisticalty and P<0.05 considered significant.Results: No significant reduction were observed between mean of changes in total cholestrol, HDL-C, triglycerid and LDL-C in female group (p<0.05). In this period after adjusting for non pharmacological treatment, only in male group (46 case) with CAD decrease in LDL-C was observed (11.2% vs 2.8%), but in female group, it was 4.8% in VITAMIN E group vs 2.4% in controls. Discussion: It can be concluded that 100mg VITAMIN E per day has no beneficil effect on plasma lipid levels. Decrease in LDL-C level of male group can be due to male hormonel effect of VITAMIN E that needs further investigation.

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    Cite

    APA: Copy

    NOUGH, H., & RAFIEI, M.. (2004). EFFECTIVENESS OF ORAL VITAMIN E ON SERUM LIPOPROTEINS OF PATIENTS WITH CORONARY ARTERY DISEASE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 15(2), 107-114. SID. https://sid.ir/paper/64275/en

    Vancouver: Copy

    NOUGH H., RAFIEI M.. EFFECTIVENESS OF ORAL VITAMIN E ON SERUM LIPOPROTEINS OF PATIENTS WITH CORONARY ARTERY DISEASE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2004;15(2):107-114. Available from: https://sid.ir/paper/64275/en

    IEEE: Copy

    H. NOUGH, and M. RAFIEI, “EFFECTIVENESS OF ORAL VITAMIN E ON SERUM LIPOPROTEINS OF PATIENTS WITH CORONARY ARTERY DISEASE,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 15, no. 2, pp. 107–114, 2004, [Online]. Available: https://sid.ir/paper/64275/en

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