Effects of Short-term and Long-term Administration of Ritalin on Anxiety and Locomotor Activity: a research based on animal modeling

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Golbaghi N.; NAEIMI S.; MAHDAVI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF CLINICAL PSYCHOLOGY Year:2021 | Volume:12 | Issue:4 (48) Page(s): 92-101

Download Full-Text

View:

218

Download:

Cites:

Information Journal Paper

Title

Effects of Short-term and Long-term Administration of Ritalin on Anxiety and Locomotor Activity: a research based on animal modeling

Author(s)

Golbaghi N. | NAEIMI S. | MAHDAVI A. | Issue Writer Certificate

Keywords

Anxiety

Ritalin

Locomotor activity

Abstract

Introduction: The aim of this study was to investigate the effects of acute and chronic administration of Ritalin on some behavioral parameters such as Anxiety and Locomotor activity and its comparison between male and female rats. Method: The present study is an experimental interventional study performed on 40 adult rats. Rats were divided into 8 groups (5 Rats per group); including two control groups and six treatment groups. Control groups were given saline and treatment groups were given therapeutic doses or high doses Ritalin per day for 30 days by gavage. The effects of the drug on Anxiety and Locomotor activity were monitored by Elevated Plus Maze and Open Field respectively. Data were analyzed by one-way ANOVA and Duncan’ s test using SPSS software. Results: In the chronic test, the number of line crossing significantly was increased in the both genders of 10 mg/kg. Meanwhile, the data showed no significant change in the rate of Anxiety subsequent to the acute or chronic Ritalin administration. It is worth mentioning that female rats in high dose showed less Anxiety comparison to male counterparts. Conclusion: This study revealed that long-term use of high dose of Ritalin may lead to increasing Locomotor activity and then behavioral sensitization in both sexes. Furthermore, Ritalin has no impact on Anxiety rate in therapeutic doses.

Cites

No record.

References

No record.

Cite

APA: Copy

Golbaghi, N., NAEIMI, S., & MAHDAVI, A.. (2021). Effects of Short-term and Long-term Administration of Ritalin on Anxiety and Locomotor Activity: a research based on animal modeling. JOURNAL OF CLINICAL PSYCHOLOGY, 12(4 (48) ), 92-101. SID. https://sid.ir/paper/643106/en

Vancouver: Copy

Golbaghi N., NAEIMI S., MAHDAVI A.. Effects of Short-term and Long-term Administration of Ritalin on Anxiety and Locomotor Activity: a research based on animal modeling. JOURNAL OF CLINICAL PSYCHOLOGY[Internet]. 2021;12(4 (48) ):92-101. Available from: https://sid.ir/paper/643106/en

IEEE: Copy

N. Golbaghi, S. NAEIMI, and A. MAHDAVI, “Effects of Short-term and Long-term Administration of Ritalin on Anxiety and Locomotor Activity: a research based on animal modeling,” JOURNAL OF CLINICAL PSYCHOLOGY, vol. 12, no. 4 (48) , pp. 92–101, 2021, [Online]. Available: https://sid.ir/paper/643106/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops