STUDY OFPELARGONIUM GRAVEOLENS L.HYDROETHANOLIC LEAVES EXTRACT ON SPERMATOGENESIS IN MALE RATS INDUCED WITH LEAD ACETATE

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MIRAZI NASER; SHAHBAZI LEILA; NASRI SIMA

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Journal: Studies in Medical Sciences Year:2016 | Volume:26 | Issue:11 Page(s): 1001-1009

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Title

STUDY OFPELARGONIUM GRAVEOLENS L.HYDROETHANOLIC LEAVES EXTRACT ON SPERMATOGENESIS IN MALE RATS INDUCED WITH LEAD ACETATE

Author(s)

MIRAZI NASER | SHAHBAZI LEILA | NASRI SIMA | Issue Writer Certificate

Keywords

LEAD ACETATEQ3

TESTOSTERONEQ3

PELARGONIUM GRAVEOLENSQ2

RATQ3

Abstract

Background & Aims: Lead is a toxic heavy metal that acts as environmental pollutant. Some medicinal plants can prevent toxin injuries in body tissues. The aim of this study was to investigate the protective effect of PELARGONIUM GRAVEOLENS leaves’ extract (PGE) on spermatogenesis process in male RATs treated by lead.Materials & Methods: In this experimental study, 42 male RATs were divided randomly into 6 groups (n=7): control (taking normal saline, 0.5 ml/day), witness (taking LEAD ACETATE, 500 ppm in tap water), positive groups 1 and 2: (250 mg/Kg PGE and 500 mg/Kg PGE), treated group 1and 2 (500 ppm LEAD ACETATE in tap water+250 mg/Kg and 500mg/Kg PGE). The blood and testes tissue samples were prepared for hormonal and histological analysis. All the data were evaluated with ANOVA and Tukey test.Results: The results showed that the TESTOSTERONE serum level reduced significantly in witness group compared with the control group (P<0.001). The PGE increased TESTOSTERONE serum level in treated groups (P<0.001). LEAD ACETATE reduces the number of spermatogonia, spermatocyte, leydig and sperm cells significantly (P<0.001).Conclusion: The finding of this research revealed that PGE could inhibit the detrimental effects of LEAD ACETATE in testes. The PGE increased TESTOSTERONE hormone and number of sperms in the treated RATs.

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APA: Copy

MIRAZI, NASER, SHAHBAZI, LEILA, & NASRI, SIMA. (2016). STUDY OFPELARGONIUM GRAVEOLENS L.HYDROETHANOLIC LEAVES EXTRACT ON SPERMATOGENESIS IN MALE RATS INDUCED WITH LEAD ACETATE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 26(11), 1001-1009. SID. https://sid.ir/paper/64348/en

Vancouver: Copy

MIRAZI NASER, SHAHBAZI LEILA, NASRI SIMA. STUDY OFPELARGONIUM GRAVEOLENS L.HYDROETHANOLIC LEAVES EXTRACT ON SPERMATOGENESIS IN MALE RATS INDUCED WITH LEAD ACETATE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2016;26(11):1001-1009. Available from: https://sid.ir/paper/64348/en

IEEE: Copy

NASER MIRAZI, LEILA SHAHBAZI, and SIMA NASRI, “STUDY OFPELARGONIUM GRAVEOLENS L.HYDROETHANOLIC LEAVES EXTRACT ON SPERMATOGENESIS IN MALE RATS INDUCED WITH LEAD ACETATE,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 26, no. 11, pp. 1001–1009, 2016, [Online]. Available: https://sid.ir/paper/64348/en

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