DETERMINATION OF THE EFFICACY OF PHOSPHOMYCIN ON IMIPENEM RESISTANTKLEBSIELLA PNEUMONIAE CLINICAL ISOLATES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Darabi Narges; YOUSEFI SABER; HOSSEINI JAZANI NIMA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Studies in Medical Sciences Year:2016 | Volume:26 | Issue:11 Page(s): 960-968

Download Full-Text

Persian Verion

View:

892

Download:

Cites:

Information Journal Paper

Title

DETERMINATION OF THE EFFICACY OF PHOSPHOMYCIN ON IMIPENEM RESISTANTKLEBSIELLA PNEUMONIAE CLINICAL ISOLATES

Author(s)

Darabi Narges | YOUSEFI SABER | HOSSEINI JAZANI NIMA | Issue Writer Certificate

Keywords

KLEBSIELLA PNEUMONIAEQ2

FOSFOMYCINQ2

CLINICAL ISOLATESQ2

MULTI DRUG RESISTANTQ2

Abstract

Background & Aims: Multiple drug resistance among KLEBSIELLA PNEUMONIAE isolates is one of the most important challenges for treating of such infections. FOSFOMYCIN is a broad-spectrum peptidoglycan biosynthesis inhibitor. The purpose of this study was to evaluate the effect of FOSFOMYCIN on imipenem resistant CLINICAL ISOLATES of KLEBSIELLA PNEUMONIAE.Materials & Methods: This study included 43 isolates of imipenem resistant KLEBSIELLA PNEUMONIAE were collected from educational hospitals of Urmia and were identified by using the standard methods.Susceptibility of isolates to various antibiotics was determined by disk diffusion method. The minimum inhibitory and minimum bactericidal concentrations of FOSFOMYCIN were determined in the range of 8-1024 mg/mL.Results: All tested isolates were resistant to FOSFOMYCIN. The minimum inhibitory and bactericidal concentrations for investigated isolates were determined in the range of 512-1024 mg/mL. According to EUCAST criteria if the minimum inhibitory concentration of antibiotic for an isolate is equal or greater than 32 mg/mL, the isolates were considered as resistant to FOSFOMYCIN, so all the isolates were defined as resistant to this antibiotic.Conclusion: In spite of the fact that some of the other studies confirmed the effectiveness of this antibiotic in treatment of Enterobacteriaceae caused infections, at least in the studied area FOSFOMYCIN is inefficient for treating of infections caused by imipenem resistant KLEBSIELLA PNEUMONIAE isolates.

Cites

No record.

References

No record.

Cite

APA: Copy

Darabi, Narges, YOUSEFI, SABER, & HOSSEINI JAZANI, NIMA. (2016). DETERMINATION OF THE EFFICACY OF PHOSPHOMYCIN ON IMIPENEM RESISTANTKLEBSIELLA PNEUMONIAE CLINICAL ISOLATES. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 26(11), 960-968. SID. https://sid.ir/paper/64349/en

Vancouver: Copy

Darabi Narges, YOUSEFI SABER, HOSSEINI JAZANI NIMA. DETERMINATION OF THE EFFICACY OF PHOSPHOMYCIN ON IMIPENEM RESISTANTKLEBSIELLA PNEUMONIAE CLINICAL ISOLATES. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2016;26(11):960-968. Available from: https://sid.ir/paper/64349/en

IEEE: Copy

Narges Darabi, SABER YOUSEFI, and NIMA HOSSEINI JAZANI, “DETERMINATION OF THE EFFICACY OF PHOSPHOMYCIN ON IMIPENEM RESISTANTKLEBSIELLA PNEUMONIAE CLINICAL ISOLATES,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 26, no. 11, pp. 960–968, 2016, [Online]. Available: https://sid.ir/paper/64349/en

Related Journal Papers