THE EFFECT OF VAGINAL EVENING PRIMROSE CAPSULE ON CERVICAL RIPENING IN NULLIPAROUS WOMEN WITH POST-TERM PREGNANCY: A CLINICAL TRIAL

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SHAHALI SHADAB; KHATAMI FATEMEH; ABBASPOUR ZAHRA; GHERAGHIAN BAHMAN

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2018 | Volume:21 | Issue:8 Page(s): 30-38

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Information Journal Paper

Title

THE EFFECT OF VAGINAL EVENING PRIMROSE CAPSULE ON CERVICAL RIPENING IN NULLIPAROUS WOMEN WITH POST-TERM PREGNANCY: A CLINICAL TRIAL

Author(s)

SHAHALI SHADAB | KHATAMI FATEMEH | ABBASPOUR ZAHRA | GHERAGHIAN BAHMAN | Issue Writer Certificate

Keywords

CERVICAL RIPENINGQ1

EVENING PRIMROSE OILQ2

NULLIPAROUS WOMENQ1

POST-TERM PREGNANCYQ2

Abstract

Introductionpost term pregnancy is associated with maternal and fetal complications, including sudden death of the fetus and low Apgar score after birth. EVENING PRIMROSE OIL has been used for CERVICAL RIPENING. Despite the effects of EVENING PRIMROSE OIL on prostaglandin precursor levels and the well-established role of prostaglandins in the reconstruction of cervical matrix. This study was performed with aim to evaluate the effect of vaginal consumption of EVENING PRIMROSE OIL on CERVICAL RIPENING in NULLIPAROUS WOMEN with POST-TERM PREGNANCY. MethodsThis randomized clinical trial study was conducted on 60 pregnant women with POST-TERM PREGNANCY who referred to the maternity of Ahvaz Sina Hospital in 2017. The study groups consisted of 2 groups: vaginal capsule of 1000 mg of EVENING PRIMROSE OIL and placebo. Drug was administered after induction of labor with 10 unit oxytocin. In the intervention group, one vaginal capsule of 1000 mg of EVENING PRIMROSE OIL and in the control group, gelatin capsule as similar as the drug were used. Then, the induction of labor was started with oxytocin with similar dose (10 unit in 1000 cc serum ringer) in both groups. CERVICAL RIPENING was measured based on regular examination (every one hour). Data were collected by demographic questionnaire, timing, and bishop-score checklist. Data were analyzed by SPSS software (version 22) and independent t-test and Chi-square test. P<0. 05 was considered statistically significant. ResultsThe duration of the latent phase in both groups was 9-10. 5 hour. The duration of latent phase (p=0. 003) and bishop score (p=0. 01) had significant difference between the intervention group and the placebo group; it means more CERVICAL RIPENING in the intervention group. At second stage of measurement, bishop score ≥ 7 was 90% in the intervention group and 60% in the control group that was significantly more in the intervention group (P=0. 01). However, no significant difference between the two groups in terms of the duration of the active phase, progression rate, severity of pain, and volume of bleeding. ConclusionThe vaginal use of EVENING PRIMROSE OIL reduces the duration of the latent phase and has a positive effect on the CERVICAL RIPENING and Bishop score.

Cites

Comparison of delivery outcomes in nulliparous women in two groups of early and late amniotomy: A Clinical Trial

References

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APA: Copy

SHAHALI, SHADAB, KHATAMI, FATEMEH, ABBASPOUR, ZAHRA, & GHERAGHIAN, BAHMAN. (2018). THE EFFECT OF VAGINAL EVENING PRIMROSE CAPSULE ON CERVICAL RIPENING IN NULLIPAROUS WOMEN WITH POST-TERM PREGNANCY: A CLINICAL TRIAL. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 21(8 ), 30-38. SID. https://sid.ir/paper/64656/en

Vancouver: Copy

SHAHALI SHADAB, KHATAMI FATEMEH, ABBASPOUR ZAHRA, GHERAGHIAN BAHMAN. THE EFFECT OF VAGINAL EVENING PRIMROSE CAPSULE ON CERVICAL RIPENING IN NULLIPAROUS WOMEN WITH POST-TERM PREGNANCY: A CLINICAL TRIAL. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2018;21(8 ):30-38. Available from: https://sid.ir/paper/64656/en

IEEE: Copy

SHADAB SHAHALI, FATEMEH KHATAMI, ZAHRA ABBASPOUR, and BAHMAN GHERAGHIAN, “THE EFFECT OF VAGINAL EVENING PRIMROSE CAPSULE ON CERVICAL RIPENING IN NULLIPAROUS WOMEN WITH POST-TERM PREGNANCY: A CLINICAL TRIAL,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 21, no. 8 , pp. 30–38, 2018, [Online]. Available: https://sid.ir/paper/64656/en

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