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Information Journal Paper

Title

ASSESSMENT OF THE RELATIONSHIP BETWEEN ABSORBED SKIN DOSE AND CHRONIC DERMAL SIDE-EFFECTS OF RADIOTHERAPY IN PATIENTS WITH BREAST CANCER

Pages

  1-7

Abstract

 Introduction: Considering the increasing incidence of BREAST CANCER and patients’ delayed referral to healthcare centers, a large number of these patients are potential candidates for mastectomy and RADIOTHERAPY and will eventually suffer from early- or late-onset complications. In this study, we aimed to investigate the prevalence of chronic radiation-induced skin complications and its relation with radiation dose at skin surface in breast radiation of female patients with BREAST CANCER.Methods: Overall, 194 female patients with non-metastatic BREAST CANCER, who had undergone locoregional radiation therapy of breast and regional lymph nodes during 1999-2009, were enrolled in this cross-sectional study. CHRONIC SKIN COMPLICATIONS induced by breast radiation were assessed, based on the classification of Radiation Therapy Oncology Group (RTOG). For data analysis, Chi-square and Fisher’s exact test were performed, using SPSS version 18. P-value less than 0.05 was considered statistically significant.Results: Among 194 patients evaluated in this study, 55 subjects (28.4%) did not have any skin complications (grade 0). On the other hand, 50 (25.8%), 42 (21.6%), 16 (21.6%), and 31 (12.6%) patients had grade 1, grade 2, grade 3, and grade 4 complications, based on RTOG system, respectively. Our results showed that radiation dose at skin surface had a significant impact on the incidence of CHRONIC SKIN COMPLICATIONS. Moreover, increase in maximum skin dose was significantly correlated with CHRONIC SKIN COMPLICATIONS (P=0.009).Conclusion: As the results indicated, radiation dose at skin surface during RADIOTHERAPY is significantly correlated with CHRONIC SKIN COMPLICATIONS, and this relation should be considered in treatment planning.

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    APA: Copy

    HOMAEE SHANDIZ, FATEMEH, SALEK, RAHAM, AMIRABADI, AMIR, MOAZEN, NASRIN, & FAZL ERSI, MITRA. (2014). ASSESSMENT OF THE RELATIONSHIP BETWEEN ABSORBED SKIN DOSE AND CHRONIC DERMAL SIDE-EFFECTS OF RADIOTHERAPY IN PATIENTS WITH BREAST CANCER. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 17(116), 1-7. SID. https://sid.ir/paper/64838/en

    Vancouver: Copy

    HOMAEE SHANDIZ FATEMEH, SALEK RAHAM, AMIRABADI AMIR, MOAZEN NASRIN, FAZL ERSI MITRA. ASSESSMENT OF THE RELATIONSHIP BETWEEN ABSORBED SKIN DOSE AND CHRONIC DERMAL SIDE-EFFECTS OF RADIOTHERAPY IN PATIENTS WITH BREAST CANCER. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2014;17(116):1-7. Available from: https://sid.ir/paper/64838/en

    IEEE: Copy

    FATEMEH HOMAEE SHANDIZ, RAHAM SALEK, AMIR AMIRABADI, NASRIN MOAZEN, and MITRA FAZL ERSI, “ASSESSMENT OF THE RELATIONSHIP BETWEEN ABSORBED SKIN DOSE AND CHRONIC DERMAL SIDE-EFFECTS OF RADIOTHERAPY IN PATIENTS WITH BREAST CANCER,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 17, no. 116, pp. 1–7, 2014, [Online]. Available: https://sid.ir/paper/64838/en

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