RELATIONSHIP OF SERUM LEPTIN AND GHRELIN BETWEEN INSULIN RESISTANCE AND ANTHROPOMETRIC INDICES IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

POURGHASSEM GARGARI BAHRAM; HOUJEGHANI SHIVA; MAHBOOB SOLTAN ALI; FARZADI LAYA; SAFAEIAN ABDOLRASOUL; HAMED BEHZAD MAHDIYEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2012 | Volume:15 | Issue:1 Page(s): 1-8

Download Full-Text

Persian Verion

View:

933

Download:

Cites:

Information Journal Paper

Title

RELATIONSHIP OF SERUM LEPTIN AND GHRELIN BETWEEN INSULIN RESISTANCE AND ANTHROPOMETRIC INDICES IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Author(s)

Keywords

ANTHROPOMETRIC INDICESQ2

GHRELINQ2

INSULIN RESISTANCEQ2

LEPTINQ2

POLYCYSTIC OVARY SYNDROMEQ2

Abstract

Introduction: POLYCYSTIC OVARY SYNDROME (PCOS) is one of the prevalent diseases in women. INSULIN RESISTANCE is a predominant clinical feature in this syndrome. LEPTIN and GHRELIN have significant effects on PCOS. Studies in this field are limited with conflicting results, so this study was designed to evaluate serum LEPTIN and GHRELIN and their relationship with INSULIN RESISTANCE and ANTHROPOMETRIC INDICES in women with PCOS.Methods: This case-control study conducted with simple method sampling on 30 PCOS women and 30 healthy controls in Alzahra hospital of Tabriz in 2010. Weight, height, waist and hip circumferences, level of blood glucose, serum LEPTIN and GHRELIN were measured by standard methods. Body mass index (BMI), waist to hip ratio (WHR) and INSULIN RESISTANCE were calculated. Mean of LEPTIN, GHRELIN and their relationship between INSULIN RESISTANCE, BMI and WHR were determined by SPSS software version 11.5.Results: Mean of serum LEPTIN level and INSULIN RESISTANCE in PCOS patients were respectively 21.68±4.52 (ng/ml) and 3.47±0.54 IU and in control group were respectively 17.96±3.00 (ng/ml) and 1.81±0.31 IU (P=0.001). GHRELIN level in PCOS patients and control groups were respectively 210.33±10.98 (ng/ml) and 216.00±14.76 picomole/liter (P=0.08). There was a positive correlation between serum LEPTIN level and BMI, WHR and INSULIN RESISTANCE in PCOS patients (r=0.84, r=0.55, r=0.67, respectively, P<0.05). In controls, serum LEPTIN level was correlated with BMI and INSULIN RESISTANCE (r=0.93, r=0.77, respectively, P<0.05). No significant relationship was found between serum GHRELIN and INSULIN RESISTANCE and ANTHROPOMETRIC INDICES in patients and controls.Conclusion: Serum LEPTIN level is higher in PCOS patients but the difference of serum GHRELIN level in two groups was not significant. In women with PCOS serum LEPTIN is an effective factor in INSULIN RESISTANCE, while GHRELIN is not. In these patients, serum LEPTIN is influenced by ANTHROPOMETRIC INDICES, while serum GHRELIN is not.

Cites

No record.

References

No record.

Cite

APA: Copy

POURGHASSEM GARGARI, BAHRAM, HOUJEGHANI, SHIVA, MAHBOOB, SOLTAN ALI, FARZADI, LAYA, SAFAEIAN, ABDOLRASOUL, & HAMED BEHZAD, MAHDIYEH. (2012). RELATIONSHIP OF SERUM LEPTIN AND GHRELIN BETWEEN INSULIN RESISTANCE AND ANTHROPOMETRIC INDICES IN WOMEN WITH POLYCYSTIC OVARY SYNDROME. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 15(1), 1-8. SID. https://sid.ir/paper/64878/en

Vancouver: Copy

POURGHASSEM GARGARI BAHRAM, HOUJEGHANI SHIVA, MAHBOOB SOLTAN ALI, FARZADI LAYA, SAFAEIAN ABDOLRASOUL, HAMED BEHZAD MAHDIYEH. RELATIONSHIP OF SERUM LEPTIN AND GHRELIN BETWEEN INSULIN RESISTANCE AND ANTHROPOMETRIC INDICES IN WOMEN WITH POLYCYSTIC OVARY SYNDROME. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2012;15(1):1-8. Available from: https://sid.ir/paper/64878/en

IEEE: Copy

BAHRAM POURGHASSEM GARGARI, SHIVA HOUJEGHANI, SOLTAN ALI MAHBOOB, LAYA FARZADI, ABDOLRASOUL SAFAEIAN, and MAHDIYEH HAMED BEHZAD, “RELATIONSHIP OF SERUM LEPTIN AND GHRELIN BETWEEN INSULIN RESISTANCE AND ANTHROPOMETRIC INDICES IN WOMEN WITH POLYCYSTIC OVARY SYNDROME,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 15, no. 1, pp. 1–8, 2012, [Online]. Available: https://sid.ir/paper/64878/en

Related Journal Papers