THROMBOTIC THROMBOCYTOPENIC PURPURA AND PREGNANCY AND THE OUTCOMES OF THE NEXT PREGNANCY: A CASE REPORT

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AMIRIAN MALIHEH; GHOMIAN NAYEREH; AZAD AFROOZ; MALEKI ASIEH

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Journal Paper

Paper Information

Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2016 | Volume:19 | Issue:32 Page(s): 20-24

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Title

THROMBOTIC THROMBOCYTOPENIC PURPURA AND PREGNANCY AND THE OUTCOMES OF THE NEXT PREGNANCY: A CASE REPORT

Author(s)

AMIRIAN MALIHEH | GHOMIAN NAYEREH | AZAD AFROOZ | MALEKI ASIEH | Issue Writer Certificate

Keywords

COMPLICATIONQ2

THROMBOTIC THROMBOCYTOPENIC PURPURAQ1

PREGNANCYQ2

TREATMENTQ3

Abstract

Introduction: THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) is a life-threatening disease with high prevalence of 5% in PREGNANCY which causes Thrombocytopenia. Since PREGNANCY is a known trigger of TTP attacks, pregnant women are at risk of recurrence. Prompt diagnosis and TREATMENT before 20 weeks gestation is important and is associated with positive outcomes. In this study, a pregnant woman with TTP in her second and third pregnancies is introduced. This study was performed with aim to introduce the patient and review the most recent management and TREATMENT of TTP in PREGNANCY and prenatal counseling in patients who have a history of TTP.Case presentation: The patient is a 28-years-old woman (g3p1d1ab1). Her first PREGNANCY was ended with spontaneous abortion at 6 weeks and in second PREGNANCY, she had a cesarean section at 28 weeks gestation due to HELLP syndrome and eclampsia. After the surgery with diagnosis of TTP, plasmapheresis was performed. In current PREGNANCY at 36 weeks gestation, cesarean section was performed with primary diagnosis of HELLP syndrome; due to a drop in platelet count after surgery and observation of schistocytosis in peripheral blood smear, with diagnosis of TTP, daily plasmapheresis was done until the platelet count achieved above 100000 and the patient was discharged with good general condition.Conclusion: Since PREGNANCY is a known trigger of TTP episodes, follow-up of patients with TTP in next PREGNANCY and control of 13 factor and differentiating of congenital and acquired disease is essential; thus the risk of recurrence of maternal and fetal COMPLICATIONs are greatly reduced.

Cites

Frequency of Protein C, S and Antithrombin III Deficiency and Presence of Antibodies of Antiphospholipid Syndrome in Women with Recurrent Abortion

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APA: Copy

AMIRIAN, MALIHEH, GHOMIAN, NAYEREH, AZAD, AFROOZ, & MALEKI, ASIEH. (2016). THROMBOTIC THROMBOCYTOPENIC PURPURA AND PREGNANCY AND THE OUTCOMES OF THE NEXT PREGNANCY: A CASE REPORT. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 19(32), 20-24. SID. https://sid.ir/paper/64979/en

Vancouver: Copy

AMIRIAN MALIHEH, GHOMIAN NAYEREH, AZAD AFROOZ, MALEKI ASIEH. THROMBOTIC THROMBOCYTOPENIC PURPURA AND PREGNANCY AND THE OUTCOMES OF THE NEXT PREGNANCY: A CASE REPORT. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2016;19(32):20-24. Available from: https://sid.ir/paper/64979/en

IEEE: Copy

MALIHEH AMIRIAN, NAYEREH GHOMIAN, AFROOZ AZAD, and ASIEH MALEKI, “THROMBOTIC THROMBOCYTOPENIC PURPURA AND PREGNANCY AND THE OUTCOMES OF THE NEXT PREGNANCY: A CASE REPORT,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 19, no. 32, pp. 20–24, 2016, [Online]. Available: https://sid.ir/paper/64979/en

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