EVALUATION OF RELATED FACTORS OF REMAINED DYSPLASIA AFTER TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA BY COLD KNIFE CONIZATION (LONGITUDINAL STUDY)

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YOUSEFI ZOHREH; HASANZADEH MOFRAD MALIHE; AFZALAGHAEE MONAVAR; SHARIFI NOURIEH; JAFARIAN MONA

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Paper Information

Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2014 | Volume:17 | Issue:119 Page(s): 1-8

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Title

EVALUATION OF RELATED FACTORS OF REMAINED DYSPLASIA AFTER TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA BY COLD KNIFE CONIZATION (LONGITUDINAL STUDY)

Author(s)

Keywords

CERVICAL CONIZATIONQ2

DYSPLASIAQ2

INQ2

SITU CERVICAL CANCERQ2

INVASIVE CERVICAL CARCINOMAQ2

SCCQ2

Abstract

Introduction: Basic treatment of patients with cervical INtraepithelial neoplasia is prevention of regress to INvasive carcinoma. One of the treatment methods of these patients is conization. This study was performed with the aim to evaluate the related factors of remained DYSPLASIA after treatment of cervical INtraepithelial neoplasia (CIN) by cold knife conization.Methods: This Cohort study was performed on 25 patients with cervical DYSPLASIA who were diagnosed IN colposcopy and underwent cold knife conization with INdication of conization IN 2013. Based on the results of conization, hysterectomy was performed for the patients with high grade DYSPLASIA, IN-situ INtraepithelial cancer, microscopic INvasive cancer and positive margin specimens. Histology results of these patients were compared to pathologic result of the patients with DYSPLASIA and negative margin conization who underwent conization for other reasons. Finally, the factors of remained DYSPLASIA after treatment of CIN with cold knife conization were evaluated. Data was analyzed using statistical SPSS software (version 17) and T-test and Mann-Whitney test. P≤ 0.05 was considered significant.Results: Among 25 patients, only one case of conization specimen margin was positive for DYSPLASIA that was appeared to be INvasive Squamous cell carcinoma IN performed hysterectomy. Other 11 patients who despite negative margin underwent hysterectomy, 4 patients (36.3%) have high grade DYSPLASIA (CIN III), 1 patient (9%) have low grade DYSPLASIA (CIN I) and 6 patients (54.5%) were free of remained DYSPLASIA IN cervical pathology bioopsy after conization. The results showed that severity of cervical DYSPLASIA with remained disease after conization is the factor of remained DYSPLASIA after treatment of CIN.Conclusion: Severity of DYSPLASIA is an effective prognostic factor patients IN the possibility of remained DYSPLASIA after conization IN patients with cervical DYSPLASIA, thus, close follow-up of these patients is recommended.

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References

PREVALENCE AND RISK FACTORS FOR RESIDUAL CERVICAL NEOPLASIA IN SUBSEQUENT HYSTERECTOMY FALLOWING LEEP OR CONIZATION

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APA: Copy

YOUSEFI, ZOHREH, HASANZADEH MOFRAD, MALIHE, AFZALAGHAEE, MONAVAR, SHARIFI, NOURIEH, & JAFARIAN, MONA. (2014). EVALUATION OF RELATED FACTORS OF REMAINED DYSPLASIA AFTER TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA BY COLD KNIFE CONIZATION (LONGITUDINAL STUDY). IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 17(119), 1-8. SID. https://sid.ir/paper/65287/en

Vancouver: Copy

YOUSEFI ZOHREH, HASANZADEH MOFRAD MALIHE, AFZALAGHAEE MONAVAR, SHARIFI NOURIEH, JAFARIAN MONA. EVALUATION OF RELATED FACTORS OF REMAINED DYSPLASIA AFTER TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA BY COLD KNIFE CONIZATION (LONGITUDINAL STUDY). IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2014;17(119):1-8. Available from: https://sid.ir/paper/65287/en

IEEE: Copy

ZOHREH YOUSEFI, MALIHE HASANZADEH MOFRAD, MONAVAR AFZALAGHAEE, NOURIEH SHARIFI, and MONA JAFARIAN, “EVALUATION OF RELATED FACTORS OF REMAINED DYSPLASIA AFTER TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA BY COLD KNIFE CONIZATION (LONGITUDINAL STUDY),” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 17, no. 119, pp. 1–8, 2014, [Online]. Available: https://sid.ir/paper/65287/en

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