EFFICACY AND SAFETY OF USING AMPLATZER DUCTAL OCCLUDER FOR TRANSCATHETER CLOSURE OF PERIMEMBRANOUS VENTRICULAR SEPTAL DEFECT IN PEDIATRICS

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GHADERIAN MEHDI; MERAJIE MAHMOOD; MORTEZAEIAN HODJJAT; AARABI MOGHADAM; MOHAMMAD YOOSEF; SHAHMOHAMMADI AKBAR

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Journal: Iranian Journal of Pediatrics Year:2015 | Volume:25 | Issue:2 Page(s): 1-6

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Title

EFFICACY AND SAFETY OF USING AMPLATZER DUCTAL OCCLUDER FOR TRANSCATHETER CLOSURE OF PERIMEMBRANOUS VENTRICULAR SEPTAL DEFECT IN PEDIATRICS

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Keywords

VENTRICULAR SEPTAL DEFECT

CAVB PROTOCOL

SEPTAL OCCLUDER DEVICE

Abstract

Background: Perimembranous VENTRICULAR SEPTAL DEFECT (PMVSD) is the most common subtype of VENTRICULAR SEPTAL DEFECTs. Transcatheter closure of PMVSD is a challenging procedure in management of moderate or large defects.Objectives: The purpose of this study was to show that transcatheter closure of perimembranous VENTRICULAR SEPTAL DEFECT with Amplatzer Ductal Occluder (ADO) is an effective and safe method.Patients and Methods: Between April 2012 and April 2013, 28 patients underwent percutaneous closure of PMVSD using ADO. After obtaining the size of VSD from the ventriculogram a device at least 2 mm larger than the narrowest diameter of VSD at right ventricular side was chosen. The device deployed after confirmation of its good position by echocardiography and left ventriculography. Follow up evaluations were done 1 month, 6 months, 12 months and yearly after discharge with transthoracic echocardiography and 12 lead electrocardiography.Results: The mean age of patients at procedure was 4.7±6.3 (range 2 to 14) years, mean weight 14.7±10.5 (range 10 to 40) kg. The mean defect size of the right ventricular side was 4.5 ± 1.6 mm. The average device size used was 7.3±3.2mm (range 4 to 12 mm). The ADOs were successfully implanted in all patients. The VSD occlusion rate was 65.7% at completion of the procedure, rising up to 79.5% at discharge and 96.4% during follow-up. Small residual shunts were seen at completion of the procedure, but they disappeared during follow-up in all but one patient. The mean follow-up period was 8.3±3.6 months (range 1 to 18 months). Complete atrioventricular block (CAVB), major complication or death was not observed in our study.Conclusions: Transcatheter closure of PMVSD with ADO in children is a safe and effective treatment associated with excellent success and closure rates, but long-term follow-up in a large number of patients would be warranted.

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APA: Copy

GHADERIAN, MEHDI, MERAJIE, MAHMOOD, MORTEZAEIAN, HODJJAT, AARABI, MOGHADAM, MOHAMMAD, YOOSEF, & SHAHMOHAMMADI, AKBAR. (2015). EFFICACY AND SAFETY OF USING AMPLATZER DUCTAL OCCLUDER FOR TRANSCATHETER CLOSURE OF PERIMEMBRANOUS VENTRICULAR SEPTAL DEFECT IN PEDIATRICS. IRANIAN JOURNAL OF PEDIATRICS, 25(2), 1-6. SID. https://sid.ir/paper/665620/en

Vancouver: Copy

GHADERIAN MEHDI, MERAJIE MAHMOOD, MORTEZAEIAN HODJJAT, AARABI MOGHADAM, MOHAMMAD YOOSEF, SHAHMOHAMMADI AKBAR. EFFICACY AND SAFETY OF USING AMPLATZER DUCTAL OCCLUDER FOR TRANSCATHETER CLOSURE OF PERIMEMBRANOUS VENTRICULAR SEPTAL DEFECT IN PEDIATRICS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2015;25(2):1-6. Available from: https://sid.ir/paper/665620/en

IEEE: Copy

MEHDI GHADERIAN, MAHMOOD MERAJIE, HODJJAT MORTEZAEIAN, MOGHADAM AARABI, YOOSEF MOHAMMAD, and AKBAR SHAHMOHAMMADI, “EFFICACY AND SAFETY OF USING AMPLATZER DUCTAL OCCLUDER FOR TRANSCATHETER CLOSURE OF PERIMEMBRANOUS VENTRICULAR SEPTAL DEFECT IN PEDIATRICS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 25, no. 2, pp. 1–6, 2015, [Online]. Available: https://sid.ir/paper/665620/en

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