Effect of Sclerorhachis leptoclada hydroalcoholic extract on glucose and cholesterol levels, triglyceride, as well as Serum HDL and LDL in male diabetic rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Ghafoorian Eshghi Omid; TEHRANIPOUR MARYAM; BAHARARA JAVAD; AMINTAHERI NASTARAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Birjand University of Medical Sciences Year:2020 | Volume:27 | Issue:4 Page(s): -

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Effect of Sclerorhachis leptoclada hydroalcoholic extract on glucose and cholesterol levels, triglyceride, as well as Serum HDL and LDL in male diabetic rats

Author(s)

Ghafoorian Eshghi Omid | TEHRANIPOUR MARYAM | BAHARARA JAVAD | AMINTAHERI NASTARAN | Issue Writer Certificate

Keywords

Glucose

Hydroalcoholic Extract

Sclerorhachis Leptoclada

Abstract

Background and Aims: Diabetes is a metabolic disorder in the body. Sclerorhachis Leptoclada belongs to the chicory family and is used for the treatment of AIDS and cancer due to the antioxidant compounds in the root. Therefore, this study investigated the effect of Hydroalcoholic Extract of Sclerorhachis Leptoclada on Glucose, cholesterol, triglyceride, high density lipoprotein (HDL), and low density lipoprotein (LDL) levels in diabetic rats. Materials and Methods: This experimental study included 60 male Wistar rats that were randomly divided into 10 groups of six animals per group, including control group, treatment groups 1, 2, and 3 (healthy, treated with 150 mg/kg and 300, and 600 extracts), diabetic control group, experimental groups 1, 2, and 3 (diabetic, treated with 150 mg/kg and 300 and 600 doses of extracts), positive control group (diabetic+glibenclamide), and healthy group (healthy+glibenclamide). Blood samples were taken from the rats after one month of gavage, and the measurement of Glucose, urea, creatinine, and albumin levels were conducted in this study. Furthermore, a comparison was made between the effect of Hydroalcoholic Extract of Sclerorhachis Leptoclada and the glibenclamide (a common medicin). Eventually, the results obtained from the groups were compared using t-test and ANOVA. Results: The results showed that the administration of Hydroalcoholic Extract of Sclerorhachis Leptoclada could significantly reduce Glucose levels in the experimental groups (diabetic+extract at doses of 150, 300, 600), compared to the diabetic group (P<0. 001). In addition, the consumption of Hydroalcoholic Extract of Sclerorhachis Leptoclada in diabetic patients had hypoglycemic effects and led to a significant reduction in triglyceride, HDL, and LDL levels in diabetic rats. Conclusion: According to the results, the consumption of Hydroalcoholic Extract of Sclerorhachis Leptoclada had hypoglycemic effects and reduced significantly the serum levels of Glucose, triglyceride, and creatinine in diabetic rats.

Cites

No record.

References

No record.

Cite

APA: Copy

Ghafoorian Eshghi, Omid, TEHRANIPOUR, MARYAM, BAHARARA, JAVAD, & AMINTAHERI, NASTARAN. (2020). Effect of Sclerorhachis leptoclada hydroalcoholic extract on glucose and cholesterol levels, triglyceride, as well as Serum HDL and LDL in male diabetic rats. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 27(4 ), -. SID. https://sid.ir/paper/666889/en

Vancouver: Copy

Ghafoorian Eshghi Omid, TEHRANIPOUR MARYAM, BAHARARA JAVAD, AMINTAHERI NASTARAN. Effect of Sclerorhachis leptoclada hydroalcoholic extract on glucose and cholesterol levels, triglyceride, as well as Serum HDL and LDL in male diabetic rats. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(4 ):-. Available from: https://sid.ir/paper/666889/en

IEEE: Copy

Omid Ghafoorian Eshghi, MARYAM TEHRANIPOUR, JAVAD BAHARARA, and NASTARAN AMINTAHERI, “Effect of Sclerorhachis leptoclada hydroalcoholic extract on glucose and cholesterol levels, triglyceride, as well as Serum HDL and LDL in male diabetic rats,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 4 , pp. –, 2020, [Online]. Available: https://sid.ir/paper/666889/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops