مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN IN MIGRAINE PATIENTS

Pages

  477-482

Abstract

 Background: Migarine is the most common HEADACHE around the world including Iran. In recent years, VITAMIN D deficiency has been shown to a global health problem. A few studies have been determined inverse association between serum levels of VITAMIN D with a HEADACHE. So, in this study, we investigated the effect of VITAMIN D supplementation on symptoms and C-REACTIVE PROTEIN (CRP) among patients with MIGRAINE.Materials and Methods: This study was randomized, double-blind, and controlled-placebo clinical trial. Sixty-five MIGRAINE patients aged 10-61 years were included for analysis. VITAMIN D was administrated for 10 weeks with 50, 000 IU dosage of VITAMIN D per week. Multivariate analysis of covariate and univariate analysis of covariate were done to determine the effects of VITAMIN D supplementation on symptoms, including severity, duration, frequency of HEADACHE, and the HEADACHE diary result (HDR).Results: Mean HEADACHE frequency and HDR had significant difference among two groups (5.9±7.0 vs.7.0±6.0, P=0.06 and 85.0±134.2 vs.132.1±147.1, P=0.04). But, a mean difference of HEADACHE frequency was marginally significant (P=0.06). These values were lower among the intervention group compared to placebo group. The association was not observed between CRP with MIGRAINE disease.Conclusion: In this study, we shown VITAMIN D supplementation may be useful in decreasing frequency of HEADACHE attacks and HDR among patients with MIGRAINE.

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    Cite

    APA: Copy

    MOTTAGHI, TAYEBEH, ASKARI, GHOLAMREZA, KHORVASH, FARIBORZ, & MARACY, MOHAMMAD REZA. (2015). EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN IN MIGRAINE PATIENTS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(5), 477-482. SID. https://sid.ir/paper/667003/en

    Vancouver: Copy

    MOTTAGHI TAYEBEH, ASKARI GHOLAMREZA, KHORVASH FARIBORZ, MARACY MOHAMMAD REZA. EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN IN MIGRAINE PATIENTS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(5):477-482. Available from: https://sid.ir/paper/667003/en

    IEEE: Copy

    TAYEBEH MOTTAGHI, GHOLAMREZA ASKARI, FARIBORZ KHORVASH, and MOHAMMAD REZA MARACY, “EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN IN MIGRAINE PATIENTS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 5, pp. 477–482, 2015, [Online]. Available: https://sid.ir/paper/667003/en

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