ASSESSMENT OF FETAL ANTIOXIDANT AND OXIDANT STATUS DURING DIFFERENT ANESTHESIA TECHNIQUES FOR ELECTIVE CESAREAN SECTIONS

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KARABAYIRLI SAFINAZ; KESKIN ESRA AKTEPE; KAYA AHMET; KOCA CEMILE; EREL OZCAN; DEMIRCIOGLU RUVEYDA IREM; MUSLU BUNYAMIN

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2015 | Volume:20 | Issue:8 Page(s): 739-744

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Title

ASSESSMENT OF FETAL ANTIOXIDANT AND OXIDANT STATUS DURING DIFFERENT ANESTHESIA TECHNIQUES FOR ELECTIVE CESAREAN SECTIONS

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ANESTHESIA

CESAREAN SECTION

OXIDATIVE STRESS

Abstract

Background: We aimed to investigate the effects of general, spinal and epidural ANESTHESIA on fetal total antioxidant status (TAS) and total oxidant status (TOS), and OXIDATIVE STRESS index (OSI) during elective CESAREAN SECTION in this study.Materials and Methods: Forty-seven parturients scheduled for elective CESAREAN SECTION were randomly allocated into three groups: Group spinal (n=15), group epidural (n=17), and group general (n=15), This prospective randomized study was performed in Faculty of Medicine, TurgutOzal University, Turkey. After the baby was delivered; TAS, TOS levels, and arterial blood gases parameters were analyzed in an umbilical arterial blood sample. OSI values are calculated by a ratio of TOS to the TAS.Results: The levels of TAS and TOS in umbilical arterial blood sample were not statistically different among three. However, OSI values were significantly diff erent among the three groups (P=0.042). Median OSI values is 24 (interquartile range [IQR], 2-37) in group spinal, 19 (IQR, 4-44) in group epidural, and 8 (IQR, 4-36) in group general. There was no significant difference in OSI values in the comparison of group spinal with group general and group epidural, but it was significantly lower in group general when compared with group epidural with Bonferroni correction (P= 0.017). Umbilical cord arterial blood gas values (pH, PaCO2, PaO2, SaO2, HCO3, and CtO2), glucose, lactate, and hemoglobin levels were similar in three groups.Conclusion: General ANESTHESIA may be more favorable than epidural in those undergoing CESAREAN SECTION when fetal oxidative status gains importance.

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APA: Copy

KARABAYIRLI, SAFINAZ, KESKIN, ESRA AKTEPE, KAYA, AHMET, KOCA, CEMILE, EREL, OZCAN, DEMIRCIOGLU, RUVEYDA IREM, & MUSLU, BUNYAMIN. (2015). ASSESSMENT OF FETAL ANTIOXIDANT AND OXIDANT STATUS DURING DIFFERENT ANESTHESIA TECHNIQUES FOR ELECTIVE CESAREAN SECTIONS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(8), 739-744. SID. https://sid.ir/paper/667038/en

Vancouver: Copy

KARABAYIRLI SAFINAZ, KESKIN ESRA AKTEPE, KAYA AHMET, KOCA CEMILE, EREL OZCAN, DEMIRCIOGLU RUVEYDA IREM, MUSLU BUNYAMIN. ASSESSMENT OF FETAL ANTIOXIDANT AND OXIDANT STATUS DURING DIFFERENT ANESTHESIA TECHNIQUES FOR ELECTIVE CESAREAN SECTIONS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(8):739-744. Available from: https://sid.ir/paper/667038/en

IEEE: Copy

SAFINAZ KARABAYIRLI, ESRA AKTEPE KESKIN, AHMET KAYA, CEMILE KOCA, OZCAN EREL, RUVEYDA IREM DEMIRCIOGLU, and BUNYAMIN MUSLU, “ASSESSMENT OF FETAL ANTIOXIDANT AND OXIDANT STATUS DURING DIFFERENT ANESTHESIA TECHNIQUES FOR ELECTIVE CESAREAN SECTIONS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 8, pp. 739–744, 2015, [Online]. Available: https://sid.ir/paper/667038/en

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