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Information Journal Paper

Title

FREQUENCY DISTRIBUTION OF GASTRO ESOPHAGEAL REFLUX DISEASE IN INHALATION INJURY: A HISTORICAL COHORT STUDY

Pages

  636-639

Abstract

 Background: There is no data on the prevalence and the association of GASTRO ESOPHAGEAL REFLUX DISEASE (GERD) with toxic fume inhalation. Therefore, we aimed to evaluate the FREQUENCY distribution of GERD symptoms among the individuals with mild respiratory disorder due to the past history of toxic fume exposure to sulfur mustard (SM).Materials and Methods: In a historical cohort study, subjects were randomly selected from 7000 patients in a database of all those who had a history of previous exposure to a single high dose of SM gas during war. The control group was randomly selected from adjacent neighbors of the patients, and two healthy male subjects were chosen per patient. In this study, we used the validated Persian translation of Mayo Gastroesophageal Reflux Questionnaire to assess the FREQUENCY distribution of reflux disease.Results: Relative FREQUENCY of GERD symptoms, was found to be significantly higher in the INHALATION INJURY patients with an odds ratio of 8.30 (95% confidence interval [CI]: 4.73-14.55), and after adjustment for cigarette smoking, tea consumption, age, and body mass index, aspirin and chronic cough the odds ratio was found to be 4.41 (95% CI: 1.61-12.07). Conclusion: The most important finding of our study was the major GERD symptoms (heartburn and/ or acid regurgitation once or more per week) among the individuals with the past history of exposure to SM toxic gas is substantially higher (4.4-fold) than normal populations.

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    APA: Copy

    KARBASI, ASHRAF, ALIANNEJAD, RASOUL, GHANEI, MOSTAFA, NOORY SANAMY, MEHRAN, ALAEDDINI, FARSHID, & AMINI HARANDI, ALI. (2015). FREQUENCY DISTRIBUTION OF GASTRO ESOPHAGEAL REFLUX DISEASE IN INHALATION INJURY: A HISTORICAL COHORT STUDY. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(7), 636-639. SID. https://sid.ir/paper/667809/en

    Vancouver: Copy

    KARBASI ASHRAF, ALIANNEJAD RASOUL, GHANEI MOSTAFA, NOORY SANAMY MEHRAN, ALAEDDINI FARSHID, AMINI HARANDI ALI. FREQUENCY DISTRIBUTION OF GASTRO ESOPHAGEAL REFLUX DISEASE IN INHALATION INJURY: A HISTORICAL COHORT STUDY. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(7):636-639. Available from: https://sid.ir/paper/667809/en

    IEEE: Copy

    ASHRAF KARBASI, RASOUL ALIANNEJAD, MOSTAFA GHANEI, MEHRAN NOORY SANAMY, FARSHID ALAEDDINI, and ALI AMINI HARANDI, “FREQUENCY DISTRIBUTION OF GASTRO ESOPHAGEAL REFLUX DISEASE IN INHALATION INJURY: A HISTORICAL COHORT STUDY,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 7, pp. 636–639, 2015, [Online]. Available: https://sid.ir/paper/667809/en

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