مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

243
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

340
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

THE EFFECTS OF DRIED ROOT AQUEOUS EXTRACT OF SALVIA MILTIORRHIZA AND ITS MAJOR INGREDIENT IN ACCELERATION OF ORTHODONTIC TOOTH MOVEMENT IN RAT

Pages

  1044-1049

Abstract

 Objective(s): Salvia miltiorrhiza (SM) is a popular and classic herb in traditional Chineses medicines. The objective is to confirm the effects of aqueous extract of S. miltiorrhiza (ESM) and its main ingredient on the promotion of orthodontic tooth movement and healing of periodontal ligament in rat.Materials and Methods: Male Sprague-Dawley rats (n=150) were divided into five groups: model control group (0.5 ml/kg phosphate-buffered saline (PBS) injection), ESM group (0.75 g/kg/day of crude drugs) and DANSHENSU subgroups (250, 500, 750 mg/kg/day of body weight). All rats were administered intramuscularly into the buccal vestibular mucosa of first molar of left maxillary. The indicators such as the moving distance of orthodontic tooth, nuclear factor κB ligand (RANKL) and OSTEOPROTEGERIN (OPG) expression and OSTEOCLASTS were tested.Results: The expressions of RANKL and OPG in the treatment groups were obviously enhanced compared with control group (P<0.05). The increase rate of OPG expression was slower than that of RANKL. But, RANKL decreased conspicuously after no orthodontic pressure was applied, especially in the treatment groups (Danshengsu high dose group at day 30: 2.17 versus 3.47 of control, P<0.01). ESM groups promoted OSTEOCLASTS proliferation in the first 20 days.Conclusion: There is a relationship between RANKL/OPG ratio and the number of OSTEOCLASTS. ESM might accelerate periodontal alteration of rat orthodontic tooth via producing more OSTEOCLASTS.

Cites

References

  • No record.

    • Cite

    APA: Copy

    XIAO, LI QUN, WANG, HONG TAO, LI, YU LAN, ZENG, QING, ZHOU, E., NI, XIA, & HUAN, ZHONG PING. (2015). THE EFFECTS OF DRIED ROOT AQUEOUS EXTRACT OF SALVIA MILTIORRHIZA AND ITS MAJOR INGREDIENT IN ACCELERATION OF ORTHODONTIC TOOTH MOVEMENT IN RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 18(10), 1044-1049. SID. https://sid.ir/paper/670650/en

    Vancouver: Copy

    XIAO LI QUN, WANG HONG TAO, LI YU LAN, ZENG QING, ZHOU E., NI XIA, HUAN ZHONG PING. THE EFFECTS OF DRIED ROOT AQUEOUS EXTRACT OF SALVIA MILTIORRHIZA AND ITS MAJOR INGREDIENT IN ACCELERATION OF ORTHODONTIC TOOTH MOVEMENT IN RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2015;18(10):1044-1049. Available from: https://sid.ir/paper/670650/en

    IEEE: Copy

    LI QUN XIAO, HONG TAO WANG, YU LAN LI, QING ZENG, E. ZHOU, XIA NI, and ZHONG PING HUAN, “THE EFFECTS OF DRIED ROOT AQUEOUS EXTRACT OF SALVIA MILTIORRHIZA AND ITS MAJOR INGREDIENT IN ACCELERATION OF ORTHODONTIC TOOTH MOVEMENT IN RAT,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 18, no. 10, pp. 1044–1049, 2015, [Online]. Available: https://sid.ir/paper/670650/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button