PROTECTIVE EFFECT OF ROYAL JELLY ONIN VITRO FERTILIZATION (IVF) IN MALE MICE TREATED WITH OXYMETHOLONE

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ZAHMATKESH ENSIEH; NAJAFI GHOLAMREZA; NEJATI VAHID

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Journal Paper

Paper Information

Journal: Cell Journal (Yakhteh) Year:2015 | Volume:17 | Issue:3 (67) Page(s): 569-575

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Title

PROTECTIVE EFFECT OF ROYAL JELLY ONIN VITRO FERTILIZATION (IVF) IN MALE MICE TREATED WITH OXYMETHOLONE

Author(s)

ZAHMATKESH ENSIEH | NAJAFI GHOLAMREZA | NEJATI VAHID | Issue Writer Certificate

Keywords

CATALASE

EMBRYO

FERTILIZATION

OXYMETHOLONE

ROYAL JELLY

Abstract

Objective: This study aimed to investigate the effects of ROYAL JELLY (RJ) on CATALASE, total antioxidant capacity and EMBRYO development in adult mice treated with OXYMETHOLONE (OXM).Materials and Methods: In this exprimental study, 32 male and 96 female adult Naval Medical Research Institute (NMRI) mice (7-9 weeks of age) with a ratio of 1: 3 for FERTILIZATION purposes were randomly divided into 4 groups as follows: i. Control group (n=8) receiving 0.1 ml/mice saline daily by gavage for 30 day, ii. RJ group (n=8) treated with RJ at a dose of 100 mg/kg daily by gavage for 30 days, iii. OXM group (n=8) receiving OXM at the dose of 5 mg/kg daily by gavage for 30 days and iv. RJ+OXM group (n=8) receiving RJ at the dose of 100 mg/kg daily by gavage concomitant with 100 mg/kg OXM administration for 30 days.Results: Analysis revealed a significant reduction in CATALASE, total antioxidant, as well as EMBRYO development in OXM group (P<0.05). However, RJ group showed a salient recovery in the all of the above mentioned parameters and EMBRYO toxicity.Conclusion: The results of this study indicated a partially protective effect of RJ against OXM-induced EMBRYO toxicity.

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APA: Copy

ZAHMATKESH, ENSIEH, NAJAFI, GHOLAMREZA, & NEJATI, VAHID. (2015). PROTECTIVE EFFECT OF ROYAL JELLY ONIN VITRO FERTILIZATION (IVF) IN MALE MICE TREATED WITH OXYMETHOLONE. CELL JOURNAL (YAKHTEH), 17(3 (67)), 569-575. SID. https://sid.ir/paper/670999/en

Vancouver: Copy

ZAHMATKESH ENSIEH, NAJAFI GHOLAMREZA, NEJATI VAHID. PROTECTIVE EFFECT OF ROYAL JELLY ONIN VITRO FERTILIZATION (IVF) IN MALE MICE TREATED WITH OXYMETHOLONE. CELL JOURNAL (YAKHTEH)[Internet]. 2015;17(3 (67)):569-575. Available from: https://sid.ir/paper/670999/en

IEEE: Copy

ENSIEH ZAHMATKESH, GHOLAMREZA NAJAFI, and VAHID NEJATI, “PROTECTIVE EFFECT OF ROYAL JELLY ONIN VITRO FERTILIZATION (IVF) IN MALE MICE TREATED WITH OXYMETHOLONE,” CELL JOURNAL (YAKHTEH), vol. 17, no. 3 (67), pp. 569–575, 2015, [Online]. Available: https://sid.ir/paper/670999/en

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