DIAGNOSTIC VALUE OF PROVOCATIVE TEST BY INSULIN COMBINED WITH CLONIDINE FOR GROWTH HORMONE DEFICIENCY IN CHILDREN

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GUO CHENG; CHEN LI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Journal of Pediatrics Year:2013 | Volume:23 | Issue:3 Page(s): 315-320

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Information Journal Paper

Title

DIAGNOSTIC VALUE OF PROVOCATIVE TEST BY INSULIN COMBINED WITH CLONIDINE FOR GROWTH HORMONE DEFICIENCY IN CHILDREN

Author(s)

GUO CHENG | CHEN LI | Issue Writer Certificate

Keywords

CLONIDINE

INSULIN

GROWTH HORMONE

GROWTH HORMONE DEFICIENCY

SHORT STATURE

Abstract

Objective: To evaluate the diagnostic value of provocative test by INSULIN combined with CLONIDINE for GROWTH HORMONE deficiency (GHD) during childhood.Methods: Eighty children underwent a provocative test with INSULIN(0.075U/Kg, intravenous) combined with CLONIDINE (4μg/kg, orally). Among them, 40 children underwent CLONIDINE provocative test, 40 children underwent INSULIN tolerance test (ITT) in another day.Findings: The specificity of ITT+CLONIDINE test (74%, 88%) was remarkably higher than that of ITT (48%) or CLONIDINE test (65%). ITT+CLONIDINE test had a better accuracy (75%, 85%) than that of ITT (63%) or CLONIDINE test (73%).Conclusion: We conclude that the combined CLONIDINE+insulin test is a feasible, reliable, convenient, time saving, and safe tool for evaluation of the GROWTH HORMONE (GH) axes than the CLONIDINE test or ITT.

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APA: Copy

GUO, CHENG, & CHEN, LI. (2013). DIAGNOSTIC VALUE OF PROVOCATIVE TEST BY INSULIN COMBINED WITH CLONIDINE FOR GROWTH HORMONE DEFICIENCY IN CHILDREN. IRANIAN JOURNAL OF PEDIATRICS, 23(3), 315-320. SID. https://sid.ir/paper/672127/en

Vancouver: Copy

GUO CHENG, CHEN LI. DIAGNOSTIC VALUE OF PROVOCATIVE TEST BY INSULIN COMBINED WITH CLONIDINE FOR GROWTH HORMONE DEFICIENCY IN CHILDREN. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2013;23(3):315-320. Available from: https://sid.ir/paper/672127/en

IEEE: Copy

CHENG GUO, and LI CHEN, “DIAGNOSTIC VALUE OF PROVOCATIVE TEST BY INSULIN COMBINED WITH CLONIDINE FOR GROWTH HORMONE DEFICIENCY IN CHILDREN,” IRANIAN JOURNAL OF PEDIATRICS, vol. 23, no. 3, pp. 315–320, 2013, [Online]. Available: https://sid.ir/paper/672127/en

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