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Information Journal Paper

Title

IN VIVO ANTI‐TOXOPLASMA ACTIVITY OF ARIPIPRAZOLE

Pages

  938-941

Abstract

 Objective (s): There are supportive evidences about the possible role of latent Toxoplasma. Gondii infections on the behavior and neurologic functions, such as increased dopamine levels in the brain. The aim of this study was to examine anti‐toxoplasma activity of ARIPIPRAZOLE that is an atypical antipsychotic drug in mice.Materials and Methods: Mice were randomly divided into four groups, including; control, vehicle, ARIPIPRAZOLE 10 mg/kg, and ARIPIPRAZOLE 20 mg/kg. The mice were inoculated intraperitoneally with mice brain suspension containing tissue CYSTS. At the end of second month, the number of CYSTS was counted in smears prepared from brain homogenate by optical microscope.Results: There was no significant difference between mean logarithms of brain cyst numbers of ARIPIPRAZOLE groups compared with control.Conclusion: Results indicate that in ARIPIPRAZOLE groups, the brain cystogenesis was not decrease. Further study needs to investigate the role of anti‐psychotic drugs on T. gondii.

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    • Cite

    APA: Copy

    SARAEI, MEHRZAD, SAMADZADEH, NAFISEH, KHOEINI, JAVAD, SHAHNAZI, MOJTABA, NASSIRI ASL, MARJAN, & JAHANIHASHEMI, HASAN. (2015). IN VIVO ANTI?TOXOPLASMA ACTIVITY OF ARIPIPRAZOLE. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 18(9), 938-941. SID. https://sid.ir/paper/679328/en

    Vancouver: Copy

    SARAEI MEHRZAD, SAMADZADEH NAFISEH, KHOEINI JAVAD, SHAHNAZI MOJTABA, NASSIRI ASL MARJAN, JAHANIHASHEMI HASAN. IN VIVO ANTI?TOXOPLASMA ACTIVITY OF ARIPIPRAZOLE. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2015;18(9):938-941. Available from: https://sid.ir/paper/679328/en

    IEEE: Copy

    MEHRZAD SARAEI, NAFISEH SAMADZADEH, JAVAD KHOEINI, MOJTABA SHAHNAZI, MARJAN NASSIRI ASL, and HASAN JAHANIHASHEMI, “IN VIVO ANTI?TOXOPLASMA ACTIVITY OF ARIPIPRAZOLE,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 18, no. 9, pp. 938–941, 2015, [Online]. Available: https://sid.ir/paper/679328/en

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