EFFECTS OF AEROBIC TRAINING ON MTDNA MUTATION IN HUMAN BLOOD LEUCOCYTES

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MIRZAEI B.; SALAMI F.; RAHMANINIA FARHAD; JAFARI AFSHAR; HOUSHMAND M.; SHAFA M.

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Journal: RESEARCH ON SPORT SCIENCE Year:2005 | Volume:3 | Issue:8 Page(s): 105-118

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Title

EFFECTS OF AEROBIC TRAINING ON MTDNA MUTATION IN HUMAN BLOOD LEUCOCYTES

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Keywords

MITOCHONDRIAL DNA (MTDNA)Q4

OXIDATIVE STRESSQ3

COMMON DELETIONQ3

AEROBIC TRAININGQ2

Abstract

Purpose: The aim of this study was to determine the effect of 8 weeks AEROBIC TRAINING on mtDNA deletion in human blood Leucocytes.Methods: Twenty untrained healthy and nonsmoker students (traning group: n=10, age= 20.7+ 1.5 yrs, weight= 67.7+ 10kg, BF%= 17.5+7.35 & control group: n=10, age= 21.7+1.3 yrs, weight= 78.5+ 18.5 kg, BF% = 18.2+6.4) were randomly assigned to 2 groups and participated in 8 weeks AEROBIC TRAINING program (based on 50-70% HRR, Karvonen method). Blood samples were collected before and after 8 weeks. mtDNA deletion were analyzed using multiplex polymerase chain reaction (PCR) method. Although, all subjects were fairly young and the possibility of mtDNA deletion at normal condition was unlikely, however, to be certain, all blood samples were also analyzed for detecting possible deletion and excluding those subjects who had deleted mtDNA prior to the study.Results: The finding demonstrate that there are no changes in mtDNA deletion in human leucocytes in both before and after 8 weeks AEROBIC TRAINING (P= 1.00).Conclusion: Therefore, AEROBIC TRAINING has no effect on mtDNA deletion.

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References

CORRELATION BETWEEN LACTATE AND MTDNA DELETION IN BLOOD LEUKOCYTES AFTER AN EXHAUSTIVE AEROBIC EXERCISE

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APA: Copy

MIRZAEI, B., RAHMANINIA, FARHAD, SALAMI, F., JAFARI, AFSHAR, HOUSHMAND, M., & SHAFA, M.. (2005). EFFECTS OF AEROBIC TRAINING ON MTDNA MUTATION IN HUMAN BLOOD LEUCOCYTES. RESEARCH ON SPORT SCIENCE, 3(8), 105-118. SID. https://sid.ir/paper/68154/en

Vancouver: Copy

MIRZAEI B., RAHMANINIA FARHAD, SALAMI F., JAFARI AFSHAR, HOUSHMAND M., SHAFA M.. EFFECTS OF AEROBIC TRAINING ON MTDNA MUTATION IN HUMAN BLOOD LEUCOCYTES. RESEARCH ON SPORT SCIENCE[Internet]. 2005;3(8):105-118. Available from: https://sid.ir/paper/68154/en

IEEE: Copy

B. MIRZAEI, FARHAD RAHMANINIA, F. SALAMI, AFSHAR JAFARI, M. HOUSHMAND, and M. SHAFA, “EFFECTS OF AEROBIC TRAINING ON MTDNA MUTATION IN HUMAN BLOOD LEUCOCYTES,” RESEARCH ON SPORT SCIENCE, vol. 3, no. 8, pp. 105–118, 2005, [Online]. Available: https://sid.ir/paper/68154/en

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