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Information Journal Paper

Title

LC-MS based identification of stylosin and tschimgine from fungal endophytes associated with Ferula ovina

Pages

  1565-1570

Abstract

 Objective(s): Ferula ovina is an Iranian medicinal plant. Tschimgine and Stylosin are two of its major monoterpene derivatives. In this study, we proceeded to investigate some Fungal endophytes from F. ovina that can produce plant secondary metabolites. Materials and Methods: The isolated endophytic fungi were fermented in potato dextrose broth (PDB) medium and their extracts were screened for the presence of the plant compounds by liquid chromatography-tandem mass spectrometry (LC-MS). Endophytes identification was performed by morphological and molecular methods. Three markers (ITS, LSU, and TEF1) were used for accurate molecular identification. Results: Forty isolates from 9 different genera of endophytic fungi were identified, of which two recently reported species of O. ferulica and Pithoascus persicus were able to produce Tschimgine and Stylosin. Conclusion: These fungi can be used as a substitute for the production of plant’ s medicinal compounds independent of wild populations of the source plant.

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  • Cite

    APA: Copy

    Tazik, Zahra, RAHNAMA, KAMRAN, White, James Francis, SOLTANLOO, HASSAN, Hasanpour, Maede, & IRANSHAHI, MEHRDAD. (2020). LC-MS based identification of stylosin and tschimgine from fungal endophytes associated with Ferula ovina. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 23(12), 1565-1570. SID. https://sid.ir/paper/685091/en

    Vancouver: Copy

    Tazik Zahra, RAHNAMA KAMRAN, White James Francis, SOLTANLOO HASSAN, Hasanpour Maede, IRANSHAHI MEHRDAD. LC-MS based identification of stylosin and tschimgine from fungal endophytes associated with Ferula ovina. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2020;23(12):1565-1570. Available from: https://sid.ir/paper/685091/en

    IEEE: Copy

    Zahra Tazik, KAMRAN RAHNAMA, James Francis White, HASSAN SOLTANLOO, Maede Hasanpour, and MEHRDAD IRANSHAHI, “LC-MS based identification of stylosin and tschimgine from fungal endophytes associated with Ferula ovina,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 23, no. 12, pp. 1565–1570, 2020, [Online]. Available: https://sid.ir/paper/685091/en

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