Efficacy Evaluation on the Color Doppler Ultrasound, Multislice Spiral CT Combined with Serum Markers in Diagnosis of Primary Hepatic Carcinoma

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Zhao Xiaolan; Xia Yifang; Li Chunjing; Wang Dapeng

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Journal Paper

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Journal: Iranian Journal of Public Health Year:2021 | Volume:50 | Issue:8 Page(s): 1603-1612

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Information Journal Paper

Title

Efficacy Evaluation on the Color Doppler Ultrasound, Multislice Spiral CT Combined with Serum Markers in Diagnosis of Primary Hepatic Carcinoma

Author(s)

Zhao Xiaolan | Xia Yifang | Li Chunjing | Wang Dapeng | Issue Writer Certificate

Keywords

Primary hepatic carcinoma

Ultrasound

Multislice Spiral CT

Alpha-fetoprotein receptor

Combination examination

Abstract

Background: The efficacy of color Doppler Ultrasound, Multislice Spiral CT combined with serum alpha-fetoprotein (AFP) and alpha-fetoprotein heterogeneity (AFP-L3) in the diagnosis of primary hepatic carcino-ma was evaluated. Methods: Seventy-nine patients with Primary hepatic carcinoma (PHC group) and 50 patients with benign liver lesions (benign control group) admitted in Yantaishan Hospital (Yantai, China) from January 2016 to December 2018 were selected. The liver was scanned by color Doppler Ultrasound and multiple multislice spi-ral CT. The serum AFP and AFP-L3 levels were detected by electrochemiluminescence. The value of color Doppler Ultrasound, Multislice Spiral CT combined with serum AFP and AFP-L3 in diagnosis of primary liver cancer was retrospectively analyzed. Results: The color Doppler flow imaging (CDFI) showed a high-speed and high-resistance spectrum. The serum AFP and AFP-L3 levels of patients with Primary hepatic carcinoma were significantly higher than those of the benign control group were (U=138. 000 and 155. 500, P=0. 000 and 0. 000), P<0. 01. The sensitivity, accu-racy and negative predictive value of color Doppler Ultrasound, Multislice Spiral CT combined with serum AFP and AFP-L3 examinations for diagnosis of Primary hepatic carcinoma were 96. 20, 90. 70 and 93. 18%, which was significantly improved compared with each single examination (X2=27. 888, 17. 511 and 16. 202, P=0. 000, 0. 002 and 0. 003), P<0. 01. Conclusion: Color Doppler Ultrasound, Multislice Spiral CT combined with AFP and AFP-L3 examination could significantly improve the diagnosis efficiency of Primary hepatic carcinoma, which was beneficial to early clinical diagnosis and early treatment.

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APA: Copy

Zhao, Xiaolan, Xia, Yifang, Li, Chunjing, & Wang, Dapeng. (2021). Efficacy Evaluation on the Color Doppler Ultrasound, Multislice Spiral CT Combined with Serum Markers in Diagnosis of Primary Hepatic Carcinoma. IRANIAN JOURNAL OF PUBLIC HEALTH, 50(8), 1603-1612. SID. https://sid.ir/paper/685562/en

Vancouver: Copy

Zhao Xiaolan, Xia Yifang, Li Chunjing, Wang Dapeng. Efficacy Evaluation on the Color Doppler Ultrasound, Multislice Spiral CT Combined with Serum Markers in Diagnosis of Primary Hepatic Carcinoma. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2021;50(8):1603-1612. Available from: https://sid.ir/paper/685562/en

IEEE: Copy

Xiaolan Zhao, Yifang Xia, Chunjing Li, and Dapeng Wang, “Efficacy Evaluation on the Color Doppler Ultrasound, Multislice Spiral CT Combined with Serum Markers in Diagnosis of Primary Hepatic Carcinoma,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 50, no. 8, pp. 1603–1612, 2021, [Online]. Available: https://sid.ir/paper/685562/en

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