مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

90
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

62
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

Antibacterial Activity of the Iranian Scorpion's Crude Venom (Odontobuthus bidentatus) on Gram-positive and Gram-negative Bacteria

Pages

  105-110

Abstract

 Background: The venoms of some scorpions are rich in bioactive components that may be used in the development and discovery of new antibacterial drugs. The venoms have many components, such as neurotoxins, salts, proteins and peptides with therapeutic properties, and can rapidly eliminate a broad range of bacteria. This study evaluated the anti-bacterial activity of Odontobuthus bidentatus’ crude venom against typical Gram-positive and negative bacteria, such as Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. Methods: The antibacterial effects of the crude venom were evaluated using Minimal Inhibitory Concentration (MIC) and MTT assays and its IC50 value was determined, using GraphPad software. Results: The crude venom significantly inhibited the growth of both Gram-positive and negative bacteria. Also the MTT results showed that the crude venom significantly reduced the viability of E. Coli, S. Aureus, and B. Subtilis bacteria compared with that for the controls. The IC50 values of the venom for E. coli, S. aureus, and B. subtilis were 30. 19, 17. 64, and 24. 13 µ M, respectively. Conclusion: The findings suggest that the venom of O. bidentatus scorpion has antibacterial properties. Also, our results offer preliminary clues toward the development of new antibacterial agents and new drugs with high therapeutic potentials for use in animals and humans.

Cites

References

  • No record.

    • Cite

    APA: Copy

    Keshavarz Alikhani, Hani, ZARGAN, JAMIL, BIDMESHKIPOUR, ALI, HAJI NOUR MOHAMMADI, ASHKAN, HOSSEINPOUR, MOHAMMAD, HEIDARI, AHMAD, & HAJIZADEH, ABBAS. (2020). Antibacterial Activity of the Iranian Scorpion's Crude Venom (Odontobuthus bidentatus) on Gram-positive and Gram-negative Bacteria. IRANIAN JOURNAL OF TOXICOLOGY, 14(2), 105-110. SID. https://sid.ir/paper/685683/en

    Vancouver: Copy

    Keshavarz Alikhani Hani, ZARGAN JAMIL, BIDMESHKIPOUR ALI, HAJI NOUR MOHAMMADI ASHKAN, HOSSEINPOUR MOHAMMAD, HEIDARI AHMAD, HAJIZADEH ABBAS. Antibacterial Activity of the Iranian Scorpion's Crude Venom (Odontobuthus bidentatus) on Gram-positive and Gram-negative Bacteria. IRANIAN JOURNAL OF TOXICOLOGY[Internet]. 2020;14(2):105-110. Available from: https://sid.ir/paper/685683/en

    IEEE: Copy

    Hani Keshavarz Alikhani, JAMIL ZARGAN, ALI BIDMESHKIPOUR, ASHKAN HAJI NOUR MOHAMMADI, MOHAMMAD HOSSEINPOUR, AHMAD HEIDARI, and ABBAS HAJIZADEH, “Antibacterial Activity of the Iranian Scorpion's Crude Venom (Odontobuthus bidentatus) on Gram-positive and Gram-negative Bacteria,” IRANIAN JOURNAL OF TOXICOLOGY, vol. 14, no. 2, pp. 105–110, 2020, [Online]. Available: https://sid.ir/paper/685683/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button