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Information Journal Paper

Title

PREVALENCE OF HELICOBACTER PYLORI IN BIOPSY SPECIMENS AND DETERMINING OF SENSITIVITY AND SPECIFICITY OF ITS DIAGNOSTIC METHODS

Pages

  37-40

Abstract

 Background and Aim: Helicobacter pylori (HP) infection is strongly associated with chronic gastritis, peptic and duodenal ulcer and gastric malignancy. The incidence of its infection varies between different populations. Since that this organism is related with dangerous illnesses thus, in present study 195 biopsy specimens from 17 Shahrivar hospital in Mashhad were prepared in order to determine the rate of infection between specimen.Materials and Methods: Biopsy specimens were carried to the laboratory in Stuart transport medium. After homogenization of biopsy specimens, diagnosis was performed by direct Gram staining, rapid urease test and culturing in Brucella agar (Merck) with supplements. Results: H. pylori infection was detected in 122 (62.56%) of all 195. Sensitivity and specificity of the culture was 88.24% and 100% and for rapid urease test, 87.80%, 76.60% and for direct Gram staining were 87.80%, 90.9% respectively. There was no significant difference in H. Pylori infection rates between men and women statistically (64.89% men vs. 60.4% women).Conclusion: Since H. pylori infection has relatively high prevalence, diagnosis and treatment of this infection has critical importance. This study confirms a good sensitivity and specificity for culture method. By performance of culturing, there is also a possibility for antibiotic examination of separating bacteria. We recommended the use of three methods together (microscopic examination, urease test and culture), for improving the chance of diagnosis of H. pylori infection.

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    APA: Copy

    NAKHAI MOGADDAM, M., KHAJEH KARAM ALDINI, M., MALEKZADEH, F., & KHOSHNAVAYE FUMANI, A.. (2005). PREVALENCE OF HELICOBACTER PYLORI IN BIOPSY SPECIMENS AND DETERMINING OF SENSITIVITY AND SPECIFICITY OF ITS DIAGNOSTIC METHODS. OFOGH-E-DANESH, 11(2), 37-40. SID. https://sid.ir/paper/68671/en

    Vancouver: Copy

    NAKHAI MOGADDAM M., KHAJEH KARAM ALDINI M., MALEKZADEH F., KHOSHNAVAYE FUMANI A.. PREVALENCE OF HELICOBACTER PYLORI IN BIOPSY SPECIMENS AND DETERMINING OF SENSITIVITY AND SPECIFICITY OF ITS DIAGNOSTIC METHODS. OFOGH-E-DANESH[Internet]. 2005;11(2):37-40. Available from: https://sid.ir/paper/68671/en

    IEEE: Copy

    M. NAKHAI MOGADDAM, M. KHAJEH KARAM ALDINI, F. MALEKZADEH, and A. KHOSHNAVAYE FUMANI, “PREVALENCE OF HELICOBACTER PYLORI IN BIOPSY SPECIMENS AND DETERMINING OF SENSITIVITY AND SPECIFICITY OF ITS DIAGNOSTIC METHODS,” OFOGH-E-DANESH, vol. 11, no. 2, pp. 37–40, 2005, [Online]. Available: https://sid.ir/paper/68671/en

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