REVIEW ARTICLE: A REVIEW OF ANIMAL MODELS OF ALZHEIMER'S DISEASE: A BRIEF INSIGHT INTO PHARMACOLOGIC AND GENETIC MODELS

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SALARI SAJJAD; BAGHERI MARYAM

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Journal: Physiology and Pharmacology Year:2016 | Volume:20 | Issue:1 Page(s): 5-11

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Title

REVIEW ARTICLE: A REVIEW OF ANIMAL MODELS OF ALZHEIMER'S DISEASE: A BRIEF INSIGHT INTO PHARMACOLOGIC AND GENETIC MODELS

Author(s)

SALARI SAJJAD | BAGHERI MARYAM | Issue Writer Certificate

Keywords

ALZHEIMER'S DISEASE

ANIMAL MODEL

PHARMACOLOGIC MODEL

GENETIC MODEL

Abstract

ALZHEIMER'S DISEASE (AD) is the most common form of neurodegenerative disorders. Memory loss in an alert person and impairment in the function of language, attention, perception, judgment or problem solving can occur in patients with AD. However, there are some medications in order to delay the debilitating aspects of the disease, but unfortunately, scientists could not found approaches to cure this progressive problem. Hence, in order to investigate the exact mechanisms underlying the disease and to discover novel drugs that can slow the progress or alleviate the clinical symptoms of AD, producing a model which can express the most pathophysiologic and behavioral features of the disease is a desire. Nowadays, there are different ANIMAL MODELs developed by use of pharmacologic agents and/or genetic manipulations. In this paper, we aimed to describe different ANIMAL MODELs of AD, genetic and pharmacologic, that are mostly used by researchers.

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APA: Copy

SALARI, SAJJAD, & BAGHERI, MARYAM. (2016). REVIEW ARTICLE: A REVIEW OF ANIMAL MODELS OF ALZHEIMER'S DISEASE: A BRIEF INSIGHT INTO PHARMACOLOGIC AND GENETIC MODELS. PHYSIOLOGY AND PHARMACOLOGY, 20(1), 5-11. SID. https://sid.ir/paper/687411/en

Vancouver: Copy

SALARI SAJJAD, BAGHERI MARYAM. REVIEW ARTICLE: A REVIEW OF ANIMAL MODELS OF ALZHEIMER'S DISEASE: A BRIEF INSIGHT INTO PHARMACOLOGIC AND GENETIC MODELS. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2016;20(1):5-11. Available from: https://sid.ir/paper/687411/en

IEEE: Copy

SAJJAD SALARI, and MARYAM BAGHERI, “REVIEW ARTICLE: A REVIEW OF ANIMAL MODELS OF ALZHEIMER'S DISEASE: A BRIEF INSIGHT INTO PHARMACOLOGIC AND GENETIC MODELS,” PHYSIOLOGY AND PHARMACOLOGY, vol. 20, no. 1, pp. 5–11, 2016, [Online]. Available: https://sid.ir/paper/687411/en

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