IS TYPE 2 DIABETES MELLITUS IN MECHANICALLY VENTILATED ADULT TRAUMA PATIENTS POTENTIALLY RELATED TO THE OCCURRENCE OF VENTILATOR‑ASSOCIATED PNEUMONIA?

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DARVISHI KHEZRI HADI; ALIPOUR ABBAS; EMAMI ZEYDI AMIR; FIROUZIAN ABOLFAZL; MAHMOUDI GHAHRAMAN; OMRANI NAVA MELODY

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2016 | Volume:21 | Issue:2 Page(s): 0-0

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Title

IS TYPE 2 DIABETES MELLITUS IN MECHANICALLY VENTILATED ADULT TRAUMA PATIENTS POTENTIALLY RELATED TO THE OCCURRENCE OF VENTILATOR‑ASSOCIATED PNEUMONIA?

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Keywords

DIABETES MELLITUS

INTENSIVE CARE UNIT (ICU)

TRAUMA

VENTILATOR‑ASSOCIATED PNEUMONIA (VAP)

Abstract

Background: Ventilator-associated pneumonia (VAP) is a type of lung infection that typically affects critically ill patients undergoing mechanical ventilation (MV) in the intensive care unit (ICU). Patients with type 2 DIABETES MELLITUS (T2DM) are considered to be more susceptible to several types of infections including community-acquired pneumonia. However, it is not clear whether T2DM is a risk factor for the development of VAP. The purpose of this study was to determine the risk of VAP for diabetic and nondiabetic mechanically ventilated TRAUMA patients. Materials and Methods: This study is a secondary analysis of a prospective observational study of the history of T2DM in the ICU over a period of 1 year at Imam Khomeini Hospital in Iran. A total of 186 critically ill TRAUMA patients who required at least 48 h of MV were monitored for the occurrence of VAP by their clinical pulmonary infection score (CPIS) until ICU discharge, VAP diagnosis, or death.Results: Forty-one of the 186 patients developed VAP. The median time from hospitalization to VAP was 29.09 days (95% CI: 26.27–31.9). The overall incidence of VAP was 18.82 cases per 1, 000 days of intubation (95% CI: 13.86-25.57). Risk of VAP in diabetic patients was greater than nondiabetic patients after adjustments for other potential factors [hazard ratio (HR): 10.12 [95% confidence interval (CI): 5.1–20.2); P<0.0001)].Conclusion: The findings show that T2DM is associated with a significant increase in the occurrence of VAP in mechanically ventilated adult TRAUMA patients.

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APA: Copy

DARVISHI KHEZRI, HADI, ALIPOUR, ABBAS, EMAMI ZEYDI, AMIR, FIROUZIAN, ABOLFAZL, MAHMOUDI, GHAHRAMAN, & OMRANI NAVA, MELODY. (2016). IS TYPE 2 DIABETES MELLITUS IN MECHANICALLY VENTILATED ADULT TRAUMA PATIENTS POTENTIALLY RELATED TO THE OCCURRENCE OF VENTILATOR?ASSOCIATED PNEUMONIA?. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 21(2), 0-0. SID. https://sid.ir/paper/687731/en

Vancouver: Copy

DARVISHI KHEZRI HADI, ALIPOUR ABBAS, EMAMI ZEYDI AMIR, FIROUZIAN ABOLFAZL, MAHMOUDI GHAHRAMAN, OMRANI NAVA MELODY. IS TYPE 2 DIABETES MELLITUS IN MECHANICALLY VENTILATED ADULT TRAUMA PATIENTS POTENTIALLY RELATED TO THE OCCURRENCE OF VENTILATOR?ASSOCIATED PNEUMONIA?. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2016;21(2):0-0. Available from: https://sid.ir/paper/687731/en

IEEE: Copy

HADI DARVISHI KHEZRI, ABBAS ALIPOUR, AMIR EMAMI ZEYDI, ABOLFAZL FIROUZIAN, GHAHRAMAN MAHMOUDI, and MELODY OMRANI NAVA, “IS TYPE 2 DIABETES MELLITUS IN MECHANICALLY VENTILATED ADULT TRAUMA PATIENTS POTENTIALLY RELATED TO THE OCCURRENCE OF VENTILATOR?ASSOCIATED PNEUMONIA?,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 21, no. 2, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/687731/en

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