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Information Journal Paper

Title

Acute Renal Failure and Hemolytic Uremic Syndrome in Overdose With N-acetyl Cysteine After Acetaminophen Poisoning

Pages

  0-0

Abstract

 Context: Acetylcysteine is an effective treatment for acetaminophen poisoning. The preparation and dose calculation of Acetylcysteine is associated with medical errors. The prevalence of this error is 34% globally. Case report: A 15-year-old girl took an overdose of acetaminophen in a suicide attempt. Acetylcysteine intravenous was ordered. Due to the Medication Error by the nurse, she received a 10-fold overdose of intravenous Acetylcysteine in both initial loading dose and maintenance dose, at first day. On the second day, the patient showed abdominal pain, nausea, vomiting, and elevated liver enzymes. Her hemoglobin, hematocrit, and platelet quickly decreased. Subsequently, she developed oliguria, anuria, and rising serum creatinine levels. The patient was diagnosed with uremic hemolytic syndrome. She underwent hemodialysis and was treated with plasmapheresis, blood transfusions, and platelets. Discussion: The effects of acetaminophen poisoning and Acetylcysteine overdose may be much more severe and have a greater impact on patient survival than each poisoning alone. Timely and accurate treatment measures can help prevent long-term side effects.

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    • Cite

    APA: Copy

    ASADZADEH, REZA, KHALIGHI, ZAHRA, Mamizadeh, Nahid, Hadavi, Marzieh, Ghaysouri, Abas, & Mozafari, Aliashraf. (2021). Acute Renal Failure and Hemolytic Uremic Syndrome in Overdose With N-acetyl Cysteine After Acetaminophen Poisoning. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, 13(3), 0-0. SID. https://sid.ir/paper/688218/en

    Vancouver: Copy

    ASADZADEH REZA, KHALIGHI ZAHRA, Mamizadeh Nahid, Hadavi Marzieh, Ghaysouri Abas, Mozafari Aliashraf. Acute Renal Failure and Hemolytic Uremic Syndrome in Overdose With N-acetyl Cysteine After Acetaminophen Poisoning. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY[Internet]. 2021;13(3):0-0. Available from: https://sid.ir/paper/688218/en

    IEEE: Copy

    REZA ASADZADEH, ZAHRA KHALIGHI, Nahid Mamizadeh, Marzieh Hadavi, Abas Ghaysouri, and Aliashraf Mozafari, “Acute Renal Failure and Hemolytic Uremic Syndrome in Overdose With N-acetyl Cysteine After Acetaminophen Poisoning,” THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, vol. 13, no. 3, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/688218/en

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