INVESTIGATION THE EFFECT OF CARBAMAZEPINE ON ACQUISITION PASSIVE AVOIDANCE LEARNING IN MALE RAT MODEL OF SEIZURE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHOLAMPOOR FARD FATEMEH; HEYDARIEH NASRIN; Moghadamirad Mohammad

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2016 | Volume:24 | Issue:5 Page(s): 429-439

Download Full-Text

View:

231

Download:

Cites:

Information Journal Paper

Title

INVESTIGATION THE EFFECT OF CARBAMAZEPINE ON ACQUISITION PASSIVE AVOIDANCE LEARNING IN MALE RAT MODEL OF SEIZURE

Author(s)

GHOLAMPOOR FARD FATEMEH | HEYDARIEH NASRIN | Moghadamirad Mohammad

Keywords

CARBAMAZEPINE

SEIZURE

PENTYLENETETRAZOLE

LEARNING

MEMORY

RAT

Abstract

Introduction: Epilepsy is the most common disorder of the central nerves system. Patients suffering from epilepsy can experience a wide range of neuropsychological disorders such as impaired MEMORY, disturbances in attention and information processing. Due to the effect of anticonvulsant CARBAMAZEPINE and its effect on the MEMORY and LEARNING, the aim of this study was investigating the effect of CARBAMAZEPINE on passive avoidance LEARNING in male RATs SEIZURE model.Methods: 30 male Wistar RATs with an average weight of 230±20 g were used in the study. Animals were randomly divided into 5 groups. SEIZURE was induced by administration of PENTYLENETETRAZOLE (PTZ: 60 mg/kg, ip). After induction of SEIZURE the LEARNING and MEMORY of RATs was tested in shuttle box. Latency to enter the dark room MEMORY was evaluated as indicators of LEARNING and MEMORY. The data were analyzed by one way variance analysis and Tukey’s test using SPSS.Results: PENTYLENETETRAZOLE-induced SEIZUREs (PTZ) in acquisition group significantly reduced the latency to enter the dark room (P<0.01). CARBAMAZEPINE significantly reduce the entrance time in intact RATs and kindled RATs by PTZ (P<0.05, P<0.01).Conclusion: This study showed that the administration of CARBAMAZEPINE in SEIZURE RATs can cause the increasing LEARNING and MEMORY impairments in RATs by PENTYLENETETRAZOLE.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

GHOLAMPOOR FARD, FATEMEH, HEYDARIEH, NASRIN, & Moghadamirad, Mohammad. (2016). INVESTIGATION THE EFFECT OF CARBAMAZEPINE ON ACQUISITION PASSIVE AVOIDANCE LEARNING IN MALE RAT MODEL OF SEIZURE. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 24(5), 429-439. SID. https://sid.ir/paper/688536/en

Vancouver: Copy

GHOLAMPOOR FARD FATEMEH, HEYDARIEH NASRIN, Moghadamirad Mohammad. INVESTIGATION THE EFFECT OF CARBAMAZEPINE ON ACQUISITION PASSIVE AVOIDANCE LEARNING IN MALE RAT MODEL OF SEIZURE. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;24(5):429-439. Available from: https://sid.ir/paper/688536/en

IEEE: Copy

FATEMEH GHOLAMPOOR FARD, NASRIN HEYDARIEH, and Mohammad Moghadamirad, “INVESTIGATION THE EFFECT OF CARBAMAZEPINE ON ACQUISITION PASSIVE AVOIDANCE LEARNING IN MALE RAT MODEL OF SEIZURE,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 5, pp. 429–439, 2016, [Online]. Available: https://sid.ir/paper/688536/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops