EVALUATION OF ANTI-OXIDANT ACTIVITY OF LAVANDULA ANGUSTIFOLIA USING DPPH METHOD

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SOHEILI MASOUD; KHANDAN MOHAMMADALI; SALAMI MAHMOUD

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Journal: Journal of Arak University Medical Sciences Year:2017 | Volume:19 | Issue:12 (117) Page(s): 70-77

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Title

EVALUATION OF ANTI-OXIDANT ACTIVITY OF LAVANDULA ANGUSTIFOLIA USING DPPH METHOD

Author(s)

SOHEILI MASOUD | KHANDAN MOHAMMADALI | SALAMI MAHMOUD | Issue Writer Certificate

Keywords

ANTI- OXIDANTQ1

AQUEOUS EXTRACTQ2

LAVANDULA ANGUSTIFOLIAQ1

METABOLIC DISORDERSQ1

Abstract

Background: Stress oxidative factors are known to causes diseases resulting from METABOLIC DISORDERS. Therefore, preventing, or at least decreasing the amount of these factors may have a positive impact on prevention or improvement of the metabolic problems. Recently, the herbal medicines are more considered due to more effectiveness. We designed the present study to evaluate ANTI- OXIDANT effect of AQUEOUS EXTRACT of lavender (Lavandula angustifolia).Materials and Methods: For extract preparation, the dry aerial part of lavender mixed with boiling water for 4 hours and then the container was filtered and condensed in a bain marie. Finally, the extract was powdered by freeze dryer. The anti-oxidant activities of the herbal medicine samples in 5, 10, 20 and 40 ppm concentrations were determined via DPPH method. This method is based on free radical scavenging of 2, 2- dipheny L-1-picrylhydrazy (DPPH) reflected in the color and absorbance changes in spectrophotometery method in 520 nm. Finally the IC50 was calculated and compared with that of for vitamin C as a standard.Results: All doses of the AQUEOUS EXTRACT of the lavender showed dose- dependent potent antioxidant activity, So that, their differences were significant compared to control sample. The IC50 of the herbal medicine was 24.66 ppm that was less than the vitamin C of 2.3 ppm.Conclusion: As a potent anti-oxidant, the lavender AQUEOUS EXTRACT can be effective in treatment of metabolic diseases.

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APA: Copy

SOHEILI, MASOUD, KHANDAN, MOHAMMADALI, & SALAMI, MAHMOUD. (2017). EVALUATION OF ANTI-OXIDANT ACTIVITY OF LAVANDULA ANGUSTIFOLIA USING DPPH METHOD. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 19(12 (117)), 70-77. SID. https://sid.ir/paper/68899/en

Vancouver: Copy

SOHEILI MASOUD, KHANDAN MOHAMMADALI, SALAMI MAHMOUD. EVALUATION OF ANTI-OXIDANT ACTIVITY OF LAVANDULA ANGUSTIFOLIA USING DPPH METHOD. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2017;19(12 (117)):70-77. Available from: https://sid.ir/paper/68899/en

IEEE: Copy

MASOUD SOHEILI, MOHAMMADALI KHANDAN, and MAHMOUD SALAMI, “EVALUATION OF ANTI-OXIDANT ACTIVITY OF LAVANDULA ANGUSTIFOLIA USING DPPH METHOD,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 19, no. 12 (117), pp. 70–77, 2017, [Online]. Available: https://sid.ir/paper/68899/en

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