THE COMPARISON OF OXIDATIVE STRESS BETWEEN SMOKERS AND NONSMOKERS

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RANJBAR AKRAM; RAJABIAN H.; JAND Y.; MIRZA ZADEH E.; ESMAEELI A.; GHASEMINEZHAD S.; MALEKIRAD A.

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Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2004 | Volume:7 | Issue:3 (28) Page(s): 7-11

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Title

THE COMPARISON OF OXIDATIVE STRESS BETWEEN SMOKERS AND NONSMOKERS

Author(s)

Keywords

SMOKINGQ3

STRESS OXIDATIVEQ2

FREE RADICALSQ3

ANTIOXIDANTQ2

Abstract

Introduction: Disturbance between production of FREE RADICALS and ANTIOXIDANT defense is named oxidative stress. One of the main sources of FREE RADICALS is SMOKING that induces oxidative stress. Materials and Methods: This is a cross sectional study in which questionnaires including information such as age, sex, education, history and number of SMOKING and history of special disease were filled. Case group were smokers (n=43) who were SMOKING at least 5 years and their mean age was 37.7 year. The control group was consisted of 43 nonsmokers who were matched for age and sex. They were evaluated for oxidative stress markers including thiobarbituric acid reactive substances (TBARS) indicator of lipid peroxidation (LPO), ferric reducing ability of plasma(FRAP) indicator of total ANTIOXIDANT capacity, total thiol(SH)groups and gammaglutamyl transferase (GGT) levels in blood. Results: Results showed that induction of oxidative stress in smokers as revealed by decreased FRAP (1.89+0.03 vs. 2.24+0.04, P=0.01) and plasma SH groups (0.22+0.08 vs. 0.81+0.48, P=0.01) in comparison to those of controls. The activity of GGT and level of LPO increased but were not significant. Also the correlation between history of SMOKING and oxidative stress was not significant. Conclusion: It is concluded that SMOKING have decreased FRAP and SH groups which may put smokers at future consequences of oxidative stress. It seems that improving ANTIOXIDANT system in smokers is effective.

Cites

A SURVEY OF SOME FACTORS RELATED TO TOTAL ANTIOXIDANT CAPACITY OF SALIVA

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APA: Copy

RANJBAR, AKRAM, RAJABIAN, H., JAND, Y., MIRZA ZADEH, E., ESMAEELI, A., GHASEMINEZHAD, S., & MALEKIRAD, A.. (2004). THE COMPARISON OF OXIDATIVE STRESS BETWEEN SMOKERS AND NONSMOKERS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 7(3 (28)), 7-11. SID. https://sid.ir/paper/68955/en

Vancouver: Copy

RANJBAR AKRAM, RAJABIAN H., JAND Y., MIRZA ZADEH E., ESMAEELI A., GHASEMINEZHAD S., MALEKIRAD A.. THE COMPARISON OF OXIDATIVE STRESS BETWEEN SMOKERS AND NONSMOKERS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2004;7(3 (28)):7-11. Available from: https://sid.ir/paper/68955/en

IEEE: Copy

AKRAM RANJBAR, H. RAJABIAN, Y. JAND, E. MIRZA ZADEH, A. ESMAEELI, S. GHASEMINEZHAD, and A. MALEKIRAD, “THE COMPARISON OF OXIDATIVE STRESS BETWEEN SMOKERS AND NONSMOKERS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 7, no. 3 (28), pp. 7–11, 2004, [Online]. Available: https://sid.ir/paper/68955/en

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