METABOLIC RESPONSE TO SOY SUPPLEMENTATION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

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JAMILIAN MEHRI; SAHEBKASHAF REYHANEH

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2017 | Volume:20 | Issue:1 (118) Page(s): 14-23

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Information Journal Paper

Title

METABOLIC RESPONSE TO SOY SUPPLEMENTATION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Author(s)

JAMILIAN MEHRI | SAHEBKASHAF REYHANEH | Issue Writer Certificate

Keywords

METABOLIC PROFILESQ1

POLYCYSTIC OVARY SYNDROMEQ1

SOYQ2

Abstract

Background: We are aware of no study examining the effects of SOY supplementation on patients with POLYCYSTIC OVARY SYNDROME (PCOS).This study was conducted to evaluate the effects of SOY supplementation on METABOLIC PROFILES in women with PCOS.Materials and Methods: This randomized, double-blind, placebo-controlled clinical trial was conducted among 70 women diagnosed with PCOS. Participants were randomly divided into two groups to receive 50 mg SOY isoflavone supplements (n=35) or placebo (n=35) for 12 weeks. Fasting blood samples were taken at baseline and after a 12-week intervention to quantify related factors.Results: Intervention group, subjects who received SOY supplements had significantly decreased total serum testosterone levels (-0.2±0.4 vs. +0.1±0.3 ng/mL, p=0.01) compared with the placebo. In addition, a significant rise in plasma glutathione (+96.0±102.2 vs. +22.7±157.8 mmol/L, p=0.04) and a significant decrease in malondialdhyde levels (-0.7±0.8 vs. +0.8±2.3, p=0.001) was observed following the consumption of SOY supplements compared with the placebo.Conclusion: According to this study, SOY supplementation among PCOS women had beneficial effects on METABOLIC PROFILES.

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References

THE EFFECTS OF PHYTOESTROGEN GENISTEIN ON STEROIDOGENESIS AND ESTROGEN RECEPTOR EXPRESSION IN PORCINE GRANULOSA CELLS OF LARGE FOLLICLES

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APA: Copy

JAMILIAN, MEHRI, & SAHEBKASHAF, REYHANEH. (2017). METABOLIC RESPONSE TO SOY SUPPLEMENTATION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 20(1 (118)), 14-23. SID. https://sid.ir/paper/69140/en

Vancouver: Copy

JAMILIAN MEHRI, SAHEBKASHAF REYHANEH. METABOLIC RESPONSE TO SOY SUPPLEMENTATION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2017;20(1 (118)):14-23. Available from: https://sid.ir/paper/69140/en

IEEE: Copy

MEHRI JAMILIAN, and REYHANEH SAHEBKASHAF, “METABOLIC RESPONSE TO SOY SUPPLEMENTATION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 20, no. 1 (118), pp. 14–23, 2017, [Online]. Available: https://sid.ir/paper/69140/en

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