MULTIPLE SCLEROSIS: PATHOGENESIS, SYMPTOMS, DIAGNOSES AND CELL-BASED THERAPY

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GHASEMI NAZEM; RAZAVI SHAHNAZ; NIKZAD ELHAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Cell Journal (Yakhteh) Year:2017 | Volume:19 | Issue:1 Page(s): 1-10

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Information Journal Paper

Title

MULTIPLE SCLEROSIS: PATHOGENESIS, SYMPTOMS, DIAGNOSES AND CELL-BASED THERAPY

Author(s)

GHASEMI NAZEM | RAZAVI SHAHNAZ | NIKZAD ELHAM | Issue Writer Certificate

Keywords

MULTIPLE SCLEROSIS

CELL THERAPY

ETIOLOGY

DEMYELINATION

Abstract

MULTIPLE SCLEROSIS (MS) is a chronic inflammatory disease characterized by central nervous system (CNS) lesions that can lead to severe physical or cognitive disability as well as neurological defects. Although the ETIOLOGY and pathogenesis of MS remains unclear, the present documents illustrate that the cause of MS is multifactorial and include genetic predisposition together with environmental factors such as exposure to infectious agents, vitamin deficiencies, and smoking. These agents are able to trigger a cascade of events in the immune system which lead to neuronal cell death accompanied by nerve DEMYELINATION and neuronal dysfunction. Conventional therapies for MS are based on the use of anti-inflammatory and immunomodulatory drugs, but these treatments are not able to stop the destruction of nerve tissue. Thus, other strategies such as stem cell transplantation have been proposed for the treatment of MS.Overall, it is important that neurologists be aware of current information regarding the pathogenesis, ETIOLOGY, diagnostic criteria, and treatment of MS. Thus, this issue has been discussed according to recent available information.

Cites

Effectiveness of a Mindfulness-Based Stress Reduction Program on Functional Disability of Patients with Multiple Sclerosis

References

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APA: Copy

GHASEMI, NAZEM, RAZAVI, SHAHNAZ, & NIKZAD, ELHAM. (2017). MULTIPLE SCLEROSIS: PATHOGENESIS, SYMPTOMS, DIAGNOSES AND CELL-BASED THERAPY. CELL JOURNAL (YAKHTEH), 19(1), 1-10. SID. https://sid.ir/paper/691829/en

Vancouver: Copy

GHASEMI NAZEM, RAZAVI SHAHNAZ, NIKZAD ELHAM. MULTIPLE SCLEROSIS: PATHOGENESIS, SYMPTOMS, DIAGNOSES AND CELL-BASED THERAPY. CELL JOURNAL (YAKHTEH)[Internet]. 2017;19(1):1-10. Available from: https://sid.ir/paper/691829/en

IEEE: Copy

NAZEM GHASEMI, SHAHNAZ RAZAVI, and ELHAM NIKZAD, “MULTIPLE SCLEROSIS: PATHOGENESIS, SYMPTOMS, DIAGNOSES AND CELL-BASED THERAPY,” CELL JOURNAL (YAKHTEH), vol. 19, no. 1, pp. 1–10, 2017, [Online]. Available: https://sid.ir/paper/691829/en

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