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Information Journal Paper

Title

Review Article: The Possible Protective Effect of Resveratrol on DiazinonInduced Oxidative Stress and Hepatic Injury

Pages

  44-48

Abstract

 Diazinon, one of the most known organophosphate pesticides (OPs), has harmful effects on human organs. Acetylcholinesterase inhibition, Oxidative stress, and Inflammation are the major mechanisms of Diazinon Toxicity. Diazinon has several toxic effects on the Liver. Resveratrol (RES) is a natural polyphenol compound with antitumor, anti-diabetic, anti-obesity, anti-oxidant, anti-aging, and anti-inflammatory effects. This compound can inhibit lipid peroxidation, protein oxidation, and DNA damage. Moreover, it can induce sirt-1, PI3K/AKT, and HO-1 pathways (negative regulators of inflammatory pathways). A large body of evidence indicated that Resveratrol can attenuate Liver damage by organophosphates. In this short review, we discuss the significant role of this phytoestrogen and antioxidant against the hepatotoxic effect of Diazinon as an OP. With elucidation of the role of this supplement in reducing harmful effects of Diazinon, it can be used as a protective agent in people at risk of adverse effects of Diazinon.

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    Cite

    APA: Copy

    Mehri, Fereshteh, GOODARZI, MOHAMMAD TAGHI, & ESFAHANI, MARYAM. (2020). Review Article: The Possible Protective Effect of Resveratrol on DiazinonInduced Oxidative Stress and Hepatic Injury. AVICENNA JOURNAL OF MEDICAL BIOCHEMISTRY, 8(1), 44-48. SID. https://sid.ir/paper/692731/en

    Vancouver: Copy

    Mehri Fereshteh, GOODARZI MOHAMMAD TAGHI, ESFAHANI MARYAM. Review Article: The Possible Protective Effect of Resveratrol on DiazinonInduced Oxidative Stress and Hepatic Injury. AVICENNA JOURNAL OF MEDICAL BIOCHEMISTRY[Internet]. 2020;8(1):44-48. Available from: https://sid.ir/paper/692731/en

    IEEE: Copy

    Fereshteh Mehri, MOHAMMAD TAGHI GOODARZI, and MARYAM ESFAHANI, “Review Article: The Possible Protective Effect of Resveratrol on DiazinonInduced Oxidative Stress and Hepatic Injury,” AVICENNA JOURNAL OF MEDICAL BIOCHEMISTRY, vol. 8, no. 1, pp. 44–48, 2020, [Online]. Available: https://sid.ir/paper/692731/en

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