RESPONSE OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ENDOSTATIN TO A SESSION ACTIVITY BEFORE AND AFTER A PERIOD OF L-ARGININE SUPPLEMENTATION IN ACTIVE MEN

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MOTAHARI RAD MORTEZA; ATTARZADEH HOSSEINI SEYYED REZA

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Journal Paper

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Journal: Journal of Arak University Medical Sciences Year:2017 | Volume:20 | Issue:2 (119) Page(s): 78-88

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Title

RESPONSE OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ENDOSTATIN TO A SESSION ACTIVITY BEFORE AND AFTER A PERIOD OF L-ARGININE SUPPLEMENTATION IN ACTIVE MEN

Author(s)

MOTAHARI RAD MORTEZA | ATTARZADEH HOSSEINI SEYYED REZA | Issue Writer Certificate

Keywords

ACTIVE MENQ1

ANGIOGENESISQ1

ENDOSTATINQ1

L-ARGININEQ1

VEGFQ1

Abstract

Background: The aim of this study was to investigate the response of the most important angiogenic and angiostatic factors to a session activity before and after a period of L-ARGININE supplementation in ACTIVE MEN.Materials and Methods: In this practical and semi experimental study, 22 ACTIVE MEN were selected by convenience sampling method and they were randomly assigned into supplement (n=11) and placebo (n=11) groups. Baseline levels of VEGF and ENDOSTATIN were measured, then subjects participated an exhaustive treadmill protocol in pre-test and post-test. Immediately and two hours after the protocol, 3 cc blood samples were prepared. The subjects used daily 0.1 g.kg-1 respectively taking L-ARGININE and placebo for 14 days. The results were analyzed at the significant level (p<0.05).Results: Immediately after exercise, the levels of VEGF and VEGF to ENDOSTATIN ratio were significantly decreased in both groups compared to baseline (p≤0.05), and two hours later this change were lower than the baseline value (p≤0.05). The levels of ENDOSTATIN immediately after exercise were significantly increased in both groups compared to baseline (p≤0.05) and two hours later this change were lower than the baseline value (p≤0.05). Before and after L-ARGININE supplementation, the levels, of VEGF and VEGF to ENDOSTATIN ratio immediately after exercise were not significant(p≥0.05). while this change in the supplementation group were significantly increased two hours after exercise (p≤0.05). There was no significant change in the levels of ENDOSTATIN between two groups immediately after exercise (p≥0.05); however, these changes were significantly decreased two hours after exercise (p≤0.05).Conclusion: It seems that short-term L-ARGININE supplementation probably stimulate ANGIOGENESIS factors in response to exercise in ACTIVE MEN.

Cites

Effect of Exercise Training on Vascular Endothelial Growth Factor and Its Receptor Gene Expression in Cardiac Tissue of Type 2 Diabetic Rats

References

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APA: Copy

MOTAHARI RAD, MORTEZA, & ATTARZADEH HOSSEINI, SEYYED REZA. (2017). RESPONSE OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ENDOSTATIN TO A SESSION ACTIVITY BEFORE AND AFTER A PERIOD OF L-ARGININE SUPPLEMENTATION IN ACTIVE MEN. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 20(2 (119)), 78-88. SID. https://sid.ir/paper/69286/en

Vancouver: Copy

MOTAHARI RAD MORTEZA, ATTARZADEH HOSSEINI SEYYED REZA. RESPONSE OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ENDOSTATIN TO A SESSION ACTIVITY BEFORE AND AFTER A PERIOD OF L-ARGININE SUPPLEMENTATION IN ACTIVE MEN. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2017;20(2 (119)):78-88. Available from: https://sid.ir/paper/69286/en

IEEE: Copy

MORTEZA MOTAHARI RAD, and SEYYED REZA ATTARZADEH HOSSEINI, “RESPONSE OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ENDOSTATIN TO A SESSION ACTIVITY BEFORE AND AFTER A PERIOD OF L-ARGININE SUPPLEMENTATION IN ACTIVE MEN,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 20, no. 2 (119), pp. 78–88, 2017, [Online]. Available: https://sid.ir/paper/69286/en

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