TRANSVAGINAL ULTRASOUND COMPARED WITH SERUM β-HCG LEVEL FOR DIAGNOSIS OF ECTOPIC PREGNANCY IN SYMPTOMATIC PATIENTS

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GHATREH SAMANI FATEMEH; NOURIAN ALI; FARZADI LAYA

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Journal: Journal of Arak University Medical Sciences Year:2018 | Volume:20 | Issue:10 (127) Page(s): 90-100

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Title

TRANSVAGINAL ULTRASOUND COMPARED WITH SERUM β-HCG LEVEL FOR DIAGNOSIS OF ECTOPIC PREGNANCY IN SYMPTOMATIC PATIENTS

Author(s)

GHATREH SAMANI FATEMEH | NOURIAN ALI | FARZADI LAYA | Issue Writer Certificate

Keywords

ECTOPIC PREGNANCYQ1

HCG DISCRIMINATORY ZONEQ1

HUMAN CHORIONIC GONADOTROPINQ1

TRANSVAGINAL ULTRASOUNDQ1

Abstract

Background: Ultrasonography (US) is the most important imaging modality in detecting both intrauterine and ectopic pregnancies. This study aimed to compare serum b-hCG level with TRANSVAGINAL ULTRASOUND in symptomatic patients with ECTOPIC PREGNANCY.Materials and Methods: A total of 210 patients with definite diagnosis of ECTOPIC PREGNANCY were enrolled prospectively. All patients underwent transvaginal US by an experienced radiologist who was blind to the final status of the patient. Serum levels of b-hCG and the time gap between US examination and last menstrual period (LMP) were compared between patients with positive and negative US findings.Results: US were positive in 194 patients (92.4%) and negative in the remaining 16 patients (7.6%). The two groups were similar in terms of age (median, 31 years vs.30.5 years, respectively; p=0.57). Both the median time gap between US and LMP (median, 43 days vs.34 days, p=0.03) and serum level of b-hCG (median, 1027 mIU/ml vs.172.5 mIU/ml, p<0.001) were significantly higher in patients with positive US findings. Both differences were independent of each other in multivariate analysis. The best discriminative zone was set at a serum b-hCG level of 326 mIU/ml with a sensitivity and specificity of 86.6% and 87.5%, respectively.Conclusion: According to our findings, both the median serum level of b-hCG and time gap between US and LMP in patients with missed diagnosis of ECTOPIC PREGNANCY were significantly lower in comparison with correct diagnosis and proposed discriminative zone for serum level of b-hCG in our study is different from the previous studies though further studies are recommended especially in symptomatic patients with suspected ECTOPIC PREGNANCY.

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APA: Copy

GHATREH SAMANI, FATEMEH, NOURIAN, ALI, & FARZADI, LAYA. (2018). TRANSVAGINAL ULTRASOUND COMPARED WITH SERUM β-HCG LEVEL FOR DIAGNOSIS OF ECTOPIC PREGNANCY IN SYMPTOMATIC PATIENTS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 20(10 (127) ), 90-100. SID. https://sid.ir/paper/69305/en

Vancouver: Copy

GHATREH SAMANI FATEMEH, NOURIAN ALI, FARZADI LAYA. TRANSVAGINAL ULTRASOUND COMPARED WITH SERUM β-HCG LEVEL FOR DIAGNOSIS OF ECTOPIC PREGNANCY IN SYMPTOMATIC PATIENTS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2018;20(10 (127) ):90-100. Available from: https://sid.ir/paper/69305/en

IEEE: Copy

FATEMEH GHATREH SAMANI, ALI NOURIAN, and LAYA FARZADI, “TRANSVAGINAL ULTRASOUND COMPARED WITH SERUM β-HCG LEVEL FOR DIAGNOSIS OF ECTOPIC PREGNANCY IN SYMPTOMATIC PATIENTS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 20, no. 10 (127) , pp. 90–100, 2018, [Online]. Available: https://sid.ir/paper/69305/en

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