Opium Carcinogenicity: A Systematic Review of Experimental Studies

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Rafipour Haniyeh; MOHEBBI ELHAM; ZENDEHDEL KAZEM; MUHAMMADNEJAD SAMAD; AKBARI PARIA; Hashemi Saadeh; NOURI KOSAR; Moradkhani Fatemeh; BARATI TAHEREH; AMANPOUR SAEID

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Journal Paper

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Journal: Basic & Clinical Cancer Research Year:2020 | Volume:12 | Issue:2 Page(s): 98-108

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Title

Opium Carcinogenicity: A Systematic Review of Experimental Studies

Author(s)

Keywords

Opium

Carcinogenicity

Guideline

Neoplasm

Abstract

Several epidemiological studies have reported that regular use of Opium can be associated with an increased risk of developing cancers, including oesophageal, laryngeal, bladder, lung, and gastric cancer. In this systematic review, we aimed at investigating whether experimental studies support this finding and, if yes, how Opium consumption can cause cancer. Most of the articles that have studied Opium or its derivatives have found it as a carcinogen. However, due to the complex composition, different forms, and various ways of Opium use, further comprehensive experimental studies are required. Using modern genomic and epigenomic methods seems to help determine the molecular mechanisms underlying Opium Carcinogenicity.

Cites

Limitation of Experimental Research on Opium Consumption and Cancer Development in Human: Call for Establishment of an International Consortium (editorial)

References

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APA: Copy

Rafipour, Haniyeh, MOHEBBI, ELHAM, ZENDEHDEL, KAZEM, MUHAMMADNEJAD, SAMAD, AKBARI, PARIA, Hashemi, Saadeh, NOURI, KOSAR, Moradkhani, Fatemeh, BARATI, TAHEREH, & AMANPOUR, SAEID. (2020). Opium Carcinogenicity: A Systematic Review of Experimental Studies. BASIC & CLINICAL CANCER RESEARCH, 12(2), 98-108. SID. https://sid.ir/paper/697065/en

Vancouver: Copy

Rafipour Haniyeh, MOHEBBI ELHAM, ZENDEHDEL KAZEM, MUHAMMADNEJAD SAMAD, AKBARI PARIA, Hashemi Saadeh, NOURI KOSAR, Moradkhani Fatemeh, BARATI TAHEREH, AMANPOUR SAEID. Opium Carcinogenicity: A Systematic Review of Experimental Studies. BASIC & CLINICAL CANCER RESEARCH[Internet]. 2020;12(2):98-108. Available from: https://sid.ir/paper/697065/en

IEEE: Copy

Haniyeh Rafipour, ELHAM MOHEBBI, KAZEM ZENDEHDEL, SAMAD MUHAMMADNEJAD, PARIA AKBARI, Saadeh Hashemi, KOSAR NOURI, Fatemeh Moradkhani, TAHEREH BARATI, and SAEID AMANPOUR, “Opium Carcinogenicity: A Systematic Review of Experimental Studies,” BASIC & CLINICAL CANCER RESEARCH, vol. 12, no. 2, pp. 98–108, 2020, [Online]. Available: https://sid.ir/paper/697065/en

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