EVALUATION OF ANTI-ANGIOGENIC ACTIVITY OF SILVER NANOPARTICLE SYNTHESIS BY RUBINA TINCTORUM L (RU-AGNPS) USING CHICKEN CHORIOALLANTOIC MEMBRANE (CAM) ASSAY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHANDEHARI SARA; HOMAYOUNI TABRIZI MASOUD; ARDALAN POURAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2018 | Volume:21 | Issue:1 (130) Page(s): 82-90

Download Full-Text

Persian Verion

View:

839

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF ANTI-ANGIOGENIC ACTIVITY OF SILVER NANOPARTICLE SYNTHESIS BY RUBINA TINCTORUM L (RU-AGNPS) USING CHICKEN CHORIOALLANTOIC MEMBRANE (CAM) ASSAY

Author(s)

GHANDEHARI SARA | HOMAYOUNI TABRIZI MASOUD | ARDALAN POURAN | Issue Writer Certificate

Keywords

ANGIOGENICQ1

CHICKEN CHORIOALLANTOIC MEMBRANEQ1

RUBIA TINCTORUMQ2

SILVER NANOPARTICLESQ1

Abstract

Background: Angiogenesis occurs in physiologic (wound healing) and pathological conditions and plays an important role in tumor growth, progression and metastasis. Therefore, the inhibition of angiogenesis can be an important approach to treat cancer diseases. In recent years, the use of nanoparticles has been developed to control cancer cells and prevent tumor growth. Various studies have shown the role of nanoparticles in reducing angiogenesis and inhibition of cancer cells. So, in this study, the anti-ANGIOGENIC effect of silver nanoparticle synthesis by Rubina tinctorum L (Ru-AgNPs) on CHICKEN CHORIOALLANTOIC MEMBRANE (CAM) was investigated.Materials and Methods: In an experimental study, 60 eggs were randomly divided into 6 groups including control, laboratory control and 4 treatment groups (10 eggs/group). On the second day of incubation, a window was created on the eggs. On the 8th day, the chorioallantoic membrane of samples was treated with different concentrations of nanoparticles and on the 12th day, the image was taken from all samples. Finally, the number and length of vessels on the chorioallantoic membrane and following that weight and length of the embryo from crown to squattiest were measured. Quantitative data were analyzed using LSD-test.Results: The results showed that the Ru-AgNPs significantly reduced the length and number of blood vessels in the treated groups compared to the control group. Also, the comparison of length and weight of embryos in treated samples with control group showed that the Ru-AgNPs had an inhibitory effect on the length of the embryos, but the weight did not differ significantly in the treatment with the control group.Conclusion: Considering the inhibitory effect of the Ru-AgNPs on the angiogenesis of the chorioallantoic membrane, with further studies, this compound can be used to control and inhibit pathological angiogenesis in many diseases such as cancers.

Cites

Evaluation of (cytotoxicity and angiogenesis) of Zinc oxide nanoparticles Synthesized by aqueous extract of Origanum majorana

References

No record.

Cite

APA: Copy

GHANDEHARI, SARA, HOMAYOUNI TABRIZI, MASOUD, & ARDALAN, POURAN. (2018). EVALUATION OF ANTI-ANGIOGENIC ACTIVITY OF SILVER NANOPARTICLE SYNTHESIS BY RUBINA TINCTORUM L (RU-AGNPS) USING CHICKEN CHORIOALLANTOIC MEMBRANE (CAM) ASSAY. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 21(1 (130) ), 82-90. SID. https://sid.ir/paper/69711/en

Vancouver: Copy

GHANDEHARI SARA, HOMAYOUNI TABRIZI MASOUD, ARDALAN POURAN. EVALUATION OF ANTI-ANGIOGENIC ACTIVITY OF SILVER NANOPARTICLE SYNTHESIS BY RUBINA TINCTORUM L (RU-AGNPS) USING CHICKEN CHORIOALLANTOIC MEMBRANE (CAM) ASSAY. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2018;21(1 (130) ):82-90. Available from: https://sid.ir/paper/69711/en

IEEE: Copy

SARA GHANDEHARI, MASOUD HOMAYOUNI TABRIZI, and POURAN ARDALAN, “EVALUATION OF ANTI-ANGIOGENIC ACTIVITY OF SILVER NANOPARTICLE SYNTHESIS BY RUBINA TINCTORUM L (RU-AGNPS) USING CHICKEN CHORIOALLANTOIC MEMBRANE (CAM) ASSAY,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 21, no. 1 (130) , pp. 82–90, 2018, [Online]. Available: https://sid.ir/paper/69711/en

Related Journal Papers